- HI10a (See other available formats)
- Regulatory Status
- V CD10.7
- Other Names
- Common acute lymphoblastic leukemia antigen (CALLA), Enkephalinase, Neutral endopeptidase, Neprilysin
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.Product Details
- Human, African Green, Baboon, Capuchin monkey, Chimpanzee, Cynomolgus, Rhesus
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 787 nm.
- Product Citations
AB_2616718 (BioLegend Cat. No. 312229)
AB_2616719 (BioLegend Cat. No. 312230)
- Type II transmembrane metalloprotease family, 100 kD
B cell precursors, T cell precursors, neutrophils
- Zinc-binding metalloproteinase, B cell development
- Biologically active peptides including opioid enkephalins, bradykinin, angiotensions I & II
- Cell Type
- B cells, Neutrophils
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Shipp M, et al. 1993. Blood 82:1052.
2. Lu B, et al. 1995. J. Exp. Med. 181:2271.
- Gene ID
- 4311 View all products for this Gene ID
- Specificity (DOES NOT SHOW ON TDS):
- Specificity Alt (DOES NOT SHOW ON TDS):
- View information about CD10 on UniProt.org
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