- QA19A43 (See other available formats)
- Regulatory Status
- Other Names
- Hermes, Pgp1, H-CAM, or HUTCH
- Rat IgG2a, κ
- Ave. Rating
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- Product Citations
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CD44 is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.Product Details
- Mouse, Human
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Red Laser (633 nm)
- Product Citations
AB_2894633 (BioLegend Cat. No. 163603)
- Variable splicing of CD44 gene generates many CD44 isoforms, 80-95 kD
All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells.
- Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM.
- Hyaluronan, MIP-1β, fibronectin, collagen.
- Antigen References
- Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
- Haynes BF, et al. 1991. Cancer Cells. 3:347.
- Goldstein LA, et al. 1989. Cell. 56:1063.
- Mikecz K, et al. 1995. Nat Med. 1:558.
- Hegde V, et al. 2008. J Leukocyte Biol. 84:134.
- Liu T, et al. 2009. Biol Direct. 4:40.
- Gene ID
- 12505 View all products for this Gene ID
- Specificity (DOES NOT SHOW ON TDS):
- Specificity Alt (DOES NOT SHOW ON TDS):
- View information about CD44 on UniProt.org
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