APC anti-human CD282 (TLR2) Antibody

Pricing & Availability
Clone
W15145C (See other available formats)
Regulatory Status
RUO
Other Names
TLR2
Isotype
Mouse IgG2a, κ
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Product Citations
publications
W15145C_APC_CD282_TLR2_Antibody_121917
Human peripheral blood monocytes were stained with APC anti-human CD282 (Clone W15145C) (filled histogram) or APC mouse IgG2a, κ isotype control (open histogram).
  • W15145C_APC_CD282_TLR2_Antibody_121917
    Human peripheral blood monocytes were stained with APC anti-human CD282 (Clone W15145C) (filled histogram) or APC mouse IgG2a, κ isotype control (open histogram).
See APC spectral data
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392303 25 tests $130.00
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392304 100 tests $285.00
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Description

Toll-like receptors are type I transmembrane signaling receptors which are critical for the innate host defense to pathogens. Toll-like receptor 2 (TLR2), known as CD282, has been identified as a receptor that is central to the innate immune system's response to lipoproteins of Gram-negative bacteria and Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full length human TLR2 transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Product Citations
  1. McQueen BE, et al. 2020. Infect Immun. :88. PubMed
RRID
AB_2721442 (BioLegend Cat. No. 392303)
AB_2721443 (BioLegend Cat. No. 392304)

Antigen Details

Structure
IL-1R superfamily, TLR family, type 1 transmebrane protein, 90kD
Distribution

Monocytes, Granulocytes, endothelial and epithelial cells

Function
Activates innate host defense against bacterial pathogens
Ligand/Receptor
Microbial lipoproteins, peptidoglycans, lipoteichoic acid
Cell Type
Monocytes, Granulocytes, Endothelial cells, Epithelial cells
Biology Area
Immunology
Molecular Family
CD Molecules, Toll Like Receptors
Antigen References

1. Lien E, et al. 1999. J. Biol. Chem. 274:33419.
2. Lien E, et al. 2001. J. Biol. Chem. 276:1873.
3. Sabroe I, et al. 2002. J. Immunol. 168:4701.

Gene ID
7097 View all products for this Gene ID
UniProt
View information about CD282 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 0    Revision Date: 12/19/2017

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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