- N196/16 (See other available formats)
- Other Names
- Zinc finger protein 746, parkin-interacting sustrate, parkin-interacting substrate, ZNF746
Covance Catalog# MMS-5178
- Mouse IgG1
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Parkin-interacting substrate (PARIS), also known as zing finger protein 746 (ZNF746), accumulates in human Parkinson's disease brain. PARIS levels are controlled by parkin, and dysregulation of parkin leads to PARIS-dependent loss of dopaminergic neurons.Product Details
- Human, Mouse, Rat
- Antibody Type
- Host Species
- This monoclonal antibody was raised against a fusion protein corresponding to amino acids 1-322 (N-terminus) of human PARIS/ZNF746.
- Phosphate-buffered solution.
- The antibody was purified by affinity chromatography.
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
IHC-P - Quality tested
WB - Validated
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 µg/ml is suggested. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 µg/ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is effective in immunoblotting (WB) and immunohistochemistry (IHC-P).
AB_2564842 (BioLegend Cat. No. 820601)
- Expected MW: 60 kD
- Biology Area
- Cell Biology, Mitochondrial Function, Neuroinflammation, Neuroscience
- Molecular Family
- Enzymes and Regulators
- Gene ID
- 155061 View all products for this Gene ID
- View information about PARIS (ZNF746) on UniProt.org
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