- PMab-1 (See other available formats)
- Other Names
- T1a, gp38, stromal cell marker
- Rat IgG2a, κ
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- Product Citations
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The mucin-type glycoprotein podoplanin is thought to be involved in the development of the lymphatic vascular system. Podoplanin is named after its expression in the kidney glomerular epithelial cells (podocytes). It has a potential role in tumor progression.Product Details
- Antibody Type
- Host Species
- Peptide (38-51 amino acids of mouse podoplanin)
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
(PubMed link indicates BioLegend citation)
- Yamada S, et al. 2017. Monoclon Antib Immunodiagn Immunother. 36(2):77-79.
- 43 kD glycosylated type-1 transmembrane protein. Mucin-type protein.
Expressed on epithelial and mesothelial cells.
- Mediates effects on cell migration and adhesion through its different partners. During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation.
- Interacts with CLEC1B; the interaction is independent of CLEC1B glycosylation and activates CLEC1B; the interaction is dependent of sialic acid on O-glycans.
- Ligand Receptor
- Antigen References
- Farr A, et al. 1992. J Histochem Cytochem. 40:651.
- Schacht V, et al. 2005. Am J Pathol. 166:913.
- Gene ID
- 14726 View all products for this Gene ID
- View information about Podoplanin on UniProt.org
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