Purified anti-mouse Podoplanin Antibody

Pricing & Availability
Clone
PMab-1 (See other available formats)
Other Names
T1a, gp38, stromal cell marker
Isotype
Rat IgG2a, κ
Ave. Rating
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Product Citations
publications
PMab-1_Pure_podoplanin_Antibody_092418
Mouse cell line TE-71 was stained with podoplanin (clone PMab-1) purified (filled histogram) or Rat IgG2a, κ isotype control (clone RTK2758) purified (open histogram) followed by Goat anti-rat IgG PE.
  • PMab-1_Pure_podoplanin_Antibody_092418
    Mouse cell line TE-71 was stained with podoplanin (clone PMab-1) purified (filled histogram) or Rat IgG2a, κ isotype control (clone RTK2758) purified (open histogram) followed by Goat anti-rat IgG PE.
Cat # Size Price Quantity Avail. Save
156202 500 µg $240.00
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Description

The mucin-type glycoprotein podoplanin is thought to be involved in the development of the lymphatic vascular system. Podoplanin is named after its expression in the kidney glomerular epithelial cells (podocytes). It has a potential role in tumor progression.

Product Details
Technical data sheet

Product Details

Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Peptide (38-51 amino acids of mouse podoplanin)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Yamada S, et al. 2017. Monoclon Antib Immunodiagn Immunother. 36(2):77-79.

Antigen Details

Structure
43 kD glycosylated type-1 transmembrane protein. Mucin-type protein.
Distribution

Expressed on epithelial and mesothelial cells.

Function
Mediates effects on cell migration and adhesion through its different partners. During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation.
Interaction
Interacts with CLEC1B; the interaction is independent of CLEC1B glycosylation and activates CLEC1B; the interaction is dependent of sialic acid on O-glycans.
Ligand Receptor
CLEC1B
Antigen References
  1. Farr A, et al. 1992. J Histochem Cytochem. 40:651.
  2. Schacht V, et al. 2005. Am J Pathol. 166:913.
Gene ID
14726 View all products for this Gene ID
UniProt
View information about Podoplanin on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 10/12/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

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