Purified anti-human TCR Vβ13.1 Antibody

Pricing & Availability
Clone
H131 (See other available formats)
Other Names
T cell receptor Vβ13.1 chain, TCRBV13.1, TCRBV13
Isotype
Mouse IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
H131_Purified_TCR_Vbeta13.1_FC_1_051514
Human peripheral blood lymphocytes were stained with CD3 APC and TCR Vβ13.1 (clone H131) purified (top) or mouse IgG2b, κ purified isotype control (bottom), followed by anti-mouse IgG2b (clone RMG2b-1) FITC.
  • H131_Purified_TCR_Vbeta13.1_FC_1_051514
    Human peripheral blood lymphocytes were stained with CD3 APC and TCR Vβ13.1 (clone H131) purified (top) or mouse IgG2b, κ purified isotype control (bottom), followed by anti-mouse IgG2b (clone RMG2b-1) FITC.
  • H131_Purified_TCR_Vbeta13.1_FC_2_051514
Cat # Size Price Quantity Avail. Save
362402 100 µg $105
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

TCR Vβ13.1 is a variant of the TCR β chain. The receptor is complexed with the TCR α chain and belongs to the immunoglobulin superfamily. It is expressed on a subset of T cells and some T cell clones. Variability in the β chain is generated by Vβ, Dβ, and Jβ gene rearrangement, while variability in the α chain is generated by Vα and Jα rearrangement. TCR Vβ13.1 has been shown to be related to antigen recognition and inflammation as well as diseases, such as HIV and multiple sclerosis.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse T cell hybridoma
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Activ - Reported in the literature

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats of this clone) include: activation of TCR Vβ13.1 expressing cells1.

Application References

(PubMed link indicates BioLegend citation)
  1. Choi YW, et al. 1991. Proc. Natl. Acad. Sci. USA 88:8357.
RRID
AB_2563503 (BioLegend Cat. No. 362402)

Antigen Details

Structure
Immunoglobulin superfamily
Distribution
Subset of T cells
Function
Antigen recognition, activation of TCR Vβ13.1 bearing T cells
Ligand/Receptor
Peptide bound MHC molecules
Cell Type
T cells
Biology Area
Immunology, Adaptive Immunity
Molecular Family
TCRs
Antigen References

1. Hong J, et al. 1999. J. Immunol. 163:3530.
2. Jason J, et al. 1997. Scand. J. Immunol. 45:81.
3. Chang JC, et al. 1995. Ann. NY. Acad. Sci. 756:370.
4. Miyahara E, et al. 1999. Anticancer Res. 19:2057.
5. Usuku K, et al. 1993. Immunogenetics. 38:193.
6. Bakakos P, et al. 2002. Clin. Exp. Immunol. 129:370.

Gene ID
6957 View all products for this Gene ID
UniProt
View information about TCR Vb13.1 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 05/28/2014

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Login/Register
Forgot your password? Reset Password
Request an Account