Purified anti-human IL12RB2 Antibody

Pricing & Availability
Clone
S16020B (See other available formats)
Other Names
Interleukin-12 receptor subunit beta-2
Isotype
Mouse IgG2a, κ
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Product Citations
publications
S16020B_Pure_IL12RB2_Antibody_060618_updated
Human peripheral blood lymphocytes were activated for 3 days with PHA, and then stained with purified IL12RB2 (clone S16020b, filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
  • S16020B_Pure_IL12RB2_Antibody_060618_updated
    Human peripheral blood lymphocytes were activated for 3 days with PHA, and then stained with purified IL12RB2 (clone S16020b, filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
Cat # Size Price Quantity Avail. Save
394202 100 µg $125
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Description

IL12RB2 is a type I transmembrane protein that foms an heterodimer with IL12RB1 to produce the high affinity IL-12 receptor complex. IL12RB2 is expressed by activated T cells, TH1 cells, NK cells, B cells and plasma cells. Variants of this gene are associated with predisposition to various immune-related diseases.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human IL12RB2 transfected cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2734483 (BioLegend Cat. No. 394202)

Antigen Details

Structure
Type I transmembrane protein, 3 isoforms, foms an heterodimer with IL12RB1
Distribution

Activated T cells, TH1 cells, NK cells, B cells,  plasma cells

Function
Role in TH1 differentiation
Ligand/Receptor
IL-12
Cell Type
T cells, Th1, NK cells, B cells, Plasma cells
Biology Area
Immunology
Molecular Family
Cytokine/Chemokine Receptors
Antigen References
  1. LaMere SA, et al. 2017. J Immunol. 199:3158
  2. Prigione I, et al. 2016. Immunobiology. 221:291
  3. de Paus RA, et al. 2013. Mol Immunol. 56:380
  4. Airoldi I, et al. 2008. Blood. 112:750
Gene ID
3595 View all products for this Gene ID
UniProt
View information about IL12RB2 on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 06/05/2018

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