Purified anti-human CD50 (ICAM-3) Antibody

Pricing & Availability
CBR-IC3/1 (See other available formats)
Regulatory Status
Other Names
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes stained with purified CBR-IC3/1, followed by anti-mouse IgG FITC
  • CBR-IC3slash1_Pure_090808.jpg
    Human peripheral blood lymphocytes stained with purified CBR-IC3/1, followed by anti-mouse IgG FITC
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330002 100 µg $112
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CD50 is a 120-140 kD type I membrane protein also known as intercellular adhesion molecule 3 (ICAM-3). It is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. CD50 is a member of the Ig superfamily. It provides costimulatory signal for T cells and regulates cell adhesion through interaction with LFA-1 (CD11a/CD18, αL2) integrin.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Reported Reactivity
Baboon, Cynomolgus
Antibody Type
Host Species
SKW3 cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications include: immunoprecipitation1 and blocking1-3.

Application References

(PubMed link indicates BioLegend citation)
  1. deFougerolles AR and Springer TA, et al. 1992. J. Exp. Med. 175:185. (IP, Block)
  2. Geijtenbeek T, et al. 2000. Cell 100:575. (Block)
  3. Giannoni E, et al. 2003. J Biol. Chem. 278:36763. (Block)
Product Citations
  1. Sugden SM, et al. 2017. J Virol. 91:e02445. PubMed
AB_1186142 (BioLegend Cat. No. 330002)

Antigen Details

Ig superfamily, type I membrane protein, 130 kD

Thymocytes, T and B cells, monocytes, granulocytes, endothelial cells

Adhesion, costimulation
CD11a/CD18 (LFA-1), integrin αL2
Cell Type
B cells, Endothelial cells, Granulocytes, Monocytes, T cells, Thymocytes
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Valent P, et al. 2001. Immunol. Rev. 179:74.

Gene ID
3385 View all products for this Gene ID
View information about CD50 on UniProt.org

Related FAQs

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Go To Top Version: 3    Revision Date: 08/25/2022

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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