Purified anti-GABA(B)R2 Antibody (Previously Covance catalog# MMS-5137)

Pricing & Availability
Clone
N81/2 (See other available formats)
Other Names
Gamma-aminobutyric acid type B receptor subunit 2, gb2, GABA-BR2, GABA-B-R2, GABA-B receptor 2, GABA-B receptor, R2 subunit, G protein-coupled receptor 51, G-protein coupled receptor 51, gamma-aminobutyric acid B receptor 2
Previously
Covance Catalog# MMS-5137
Isotype
Mouse IgG1
Ave. Rating
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Product Citations
publications
N81slash2_Purified_GABABR2_Antibody_1_WB_030415
Western blot showing Clone N81/2 specificity. Lane 1: Molecular Weight Standard; Lane 2: Mouse Brain Membrane Lysate.
  • N81slash2_Purified_GABABR2_Antibody_1_WB_030415
    Western blot showing Clone N81/2 specificity. Lane 1: Molecular Weight Standard; Lane 2: Mouse Brain Membrane Lysate.
  • N81slash2_Purified_GABABR2_Antibody_2_IHC_030415
    Staining of Clone N81/2 on formalin-fixed paraffin-embedded mouse brain tissue.
Cat # Size Price Quantity Avail. Save
820501 100 µl $140.00
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Description

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho.

Product Details
Technical data sheet

Product Details

Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This monoclonal antibody was raised against a fusion protein corresponding to amino acids 862-913 (cytoplasmic C-terminus) of human GABA(B)R2.
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB, IHC

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting.

The optimal working dilution should be determined for each specific assay condition.
WB: 1:100*
IHC: 1:100

Tissue: Formalin-fixed Paraffin-embedded
Pre-treatment: Citrate
Primary incubation: 24 hours at 2-8°C

Application Notes

This antibody is effective in immunoblotting (WB) and immunohistochemistry (IHC).

*Expected MW: 105 kD

WB Positive Control: Mouse Brain Membrane Lysate

IHC Positive Control: Mouse Brain

RRID
AB_2564841 (BioLegend Cat. No. 820501)

Related FAQs

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Go To Top Version: 2    Revision Date: 07/08/2016

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

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