- A17046B (See other available formats)
- Other Names
- Chitinase-like protein 3, Chil3, Beta-N-acetylhexosaminidase Ym1, Ym1, ECF-L, Eosinophil chemotactic cytokine
- Rat IgG2a, κ
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Chitinases are hydrolytic enzymes that break down glycosidic bonds in chitin. Chitinase-like protein 3 (Chil3) hydrolyzes terminal non-reducing N-acetyl-D-hexosamine residues into N-acetyl-beta-D-hexosaminides. This protein is particular enriched in the spleen.Product Details
- Antibody Type
- Host Species
- Recombinant mouse Chil3
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2750120 (BioLegend Cat. No. 853801)
AB_2750121 (BioLegend Cat. No. 853802)
- Chil3 is a 398 amino acid protein with a molecular weight mass of ~45 kD.
Tissue distribution: Spleen, macrophages, and bone marrow-derived neutrophils.
Cellular distribution: Nucleus, endoplasmic reticulum, and secreted.
- Chil3 plays a role in hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
- Chil3 binds to chitin, lectin, and heparin.
- Cell Type
- Macrophages, Neutrophils
- Biology Area
- Cell Biology, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Enzymes and Regulators
- Antigen References
- Mesci P, et al. 2015. Brain. 138:53-68
- Wu F, et al. 2016. Parasitol Res. 115:3737
- Al-Rubaie A, et al. 2018. Respir Res. 19:114
- Gene ID
- 12655 View all products for this Gene ID
- View information about Chil3 on UniProt.org
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