Purified anti-CD18 Antibody (Previously Covance catalog# MRT-5214)

Pricing & Availability
C71/16 (See other available formats)
Other Names
Integrin beta-2, Mac-1 beta, macrophage antigen-1 beta, complement receptor C3 subunit beta, lymphocyte function associated antigen 1, cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, 2E6, LAD, Cd18, Lfa1, MF17, LCAMB, AI528527
Covance Catalog# MRT-5214
Rat Ig2a
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Product Citations
CD18 (C71/16) staining of mouse lymphocytes analyzed by flow cytometry.
  • C71slash16_Purified_CD18_Antibody_FC_022615
    CD18 (C71/16) staining of mouse lymphocytes analyzed by flow cytometry.
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830501 100 µl $234
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CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
This monoclonal antibody was raised against cell membrane glycoproteins derived from T-cell lymphoma BW5147 cells.
Phosphate-buffered solution.
The antibody was purified by affinity chromatography.
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.


Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis.

The optimal working dilution should be determined for each specific assay condition.
FC: 1:1000 - 1:10,000*

Application Notes

This antibody is effective in flow cytometry (FC).

*FC Positive Control: Mouse blood

Rat IgG2a Isotype antibody available: Catalog number: 910601

Application References

(PubMed link indicates BioLegend citation)
  1. Trowbridge IS, et al. Molecular Complexity of Leukocyte Surface Glycoproteins Related to the Macrophage Differentiation Antigen MAC-1. J. Exp. Med. 154: 1517-1524, November 1981.
AB_2564939 (BioLegend Cat. No. 830501)

Antigen Details

Biology Area
Cell Biology, Complement, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175.
3. Wilson RW, et al. 1993. J. Immunol. 151:1571.

Gene ID
16414 View all products for this Gene ID
View information about CD18 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 05/01/2016

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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