Purified anti-ADAM22 Antibody (Previously Covance catalog# MMS-5125)

Pricing & Availability
Clone
N57/2 (See other available formats)
Other Names
Disintegrin and metalloproteinase domain-containing protein 22, a disintegrin and metalloprotease domain (ADAM) 22, Metalloproteinase-disintegrin ADAM22-3, Metalloproteinase-like disintegrin-like and cysteine-rich protein 2, MDC2
Previously
Covance Catalog# MMS-5125
Isotype
Mouse IgG1
Ave. Rating
0 reviews
N57slash2_Purified_ADAM22_Antibody_WB_022615
Western blot of purified anti-ADAM22 antibody (clone N57/2). Lane 1: Molecular weight marker; Lane 2: 30 µg of rat brain membrane lysate; Lane 3: 10 µg of BSA. The blot was incubated with 10 µg/mL of the primary antibodies overnight at 4°C, followed by incubation with fluorescent labeled goat anti-mouse IgG.
  • N57slash2_Purified_ADAM22_Antibody_WB_022615
    Western blot of purified anti-ADAM22 antibody (clone N57/2). Lane 1: Molecular weight marker; Lane 2: 30 µg of rat brain membrane lysate; Lane 3: 10 µg of BSA. The blot was incubated with 10 µg/mL of the primary antibodies overnight at 4°C, followed by incubation with fluorescent labeled goat anti-mouse IgG.
  • N57slash2_Purified_ADAM22_Antibody_WB_040918
    Western blot of purified anti-ADAM22 antibody (clone N57/2). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain membrane lysate; Lane 3: 20 µg of mouse brain membrane lysate. The blot was incubated with 5 µg/mL of the primary antibodies overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
Cat # Size Price Quantity Avail. Save
831001 100 µl $140.00
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Description

ADAM22 is a member of the ADAM (a disintegrin and metalloprotease domain) family, implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. The protein is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system.

Product Details
Technical data sheet

Product Details

Reactivity
Human, Mouse, Rat
Host Species
Mouse
Immunogen
This monoclonal antibody was raised against a fusion protein corresponding to amino acids 444-526 (extracellular region) of mouse ADAM22 protein.
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 10.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody is effective in immunoblotting (WB).

Application References

(PubMed link indicates BioLegend citation)
  1. Lai M, et al. 2010. Lancet Neurol. 9:776.
Publication Library
RRID
AB_2564943 (BioLegend Cat. No. 831001)

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Go To Top Version: 3    Revision Date: 04/09/2018

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