PerCP/Cyanine5.5 anti-mouse IL-33Rα (IL1RL1, ST2) Antibody

Pricing & Availability
DIH9 (See other available formats)
Regulatory Status
Other Names
T1/ST2, ST2L, IL-1R1, T1, DER4, IL1R1
Rat IgG2a, κ
Ave. Rating
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Product Citations
ST2-FLAG transfected DO-11.10 mouse cells were stained with IL-33Ra/ST2 (clone DIH9) PerCP/Cyanine5.5 (filled histogram), or rat IgG2a, ? PerCP/Cyanine5.5 isotype control (open histogram).
  • DIH9_PerCPCyanine55_IL-33Ralpha_Antibody_101818
    ST2-FLAG transfected DO-11.10 mouse cells were stained with IL-33Ra/ST2 (clone DIH9) PerCP/Cyanine5.5 (filled histogram), or rat IgG2a, ? PerCP/Cyanine5.5 isotype control (open histogram).
Compare all formats See PerCP/Cyanine5.5 spectral data
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145311 25 µg $147
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145312 100 µg $382
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IL-33Rα, also known as ST2 or IL-1RL1, is a member of the Toll/IL-1 receptor family.  It binds IL-33 and is structurally similar to IL-1R1.  Two forms of the protein exist - a soluble form known as ST2 and a membrane anchored form known as ST2L.  The membrane form is expressed by Th2 cells and bone marrow derived mast cells, whereas the soluble form is expressed by serum-stimulated fibroblasts.

Blocking with anti-ST2 antibodies has been shown to alleviate experimental arthritis and airway inflammation.  The IL-33-ST2 axis has been reported to be important across a range of diseases including asthma, allergies, and cardiac disease.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
IL-33Rα-hFcγ1 fusion protein.
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Additional Product Notes
BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Hashiguchi M, et al. 2014. Eur. J. Immunology. (FC) PubMed
Product Citations
  1. Darzianiazizi M, et al. 2020. Int J Mol Sci. 21:00. PubMed
  2. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  3. Schmidleithner L et al. 2019. Immunity. 50(5):1232-1248 . PubMed
  4. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  5. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  6. de Lucía Finkel P, et al. 2021. Sci Rep. 11:12233. PubMed
  7. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
AB_2565635 (BioLegend Cat. No. 145311)
AB_2565636 (BioLegend Cat. No. 145312)

Antigen Details

63 kD, IL-1 receptor family member, single pass type I membrane protein

Mast cells, Th2 cells, and fibroblasts

Following interaction with IL-33, it recruits MyD88, Irak1, Irak4 and Traf6 followed by phosphorylation of the MAP/ERK pathway.
Interacts with MyD88, Irak1, Irak4 and Traf6
Cell Type
Fibroblasts, Mast cells, Th2
Biology Area
Immunology, Innate Immunity
Molecular Family
Cytokine/Chemokine Receptors
Antigen References

1. Yanagisawa K, et al. 1993. FEBS Lett. 318:83.
2. Schmitt E, et al. 1990. Cytokine 6:407.
3. Yanagisawa K, et al. 1992. FEBS Lett. 302:51.
4. Takagi T, et al. 1993. Biochim Biophys Acta. 1178:194.

Gene ID
17082 View all products for this Gene ID
View information about IL-33Ralpha on

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Go To Top Version: 2    Revision Date: 10/18/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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