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PerCP/Cyanine5.5 anti-human TCR Vβ1 Antibody

Pricing & Availability
Clone
BL37.2 (See other available formats)
Regulatory Status
RUO
Other Names
TCRBV1S1, TCRBV9
Isotype
Rat IgG1, κ
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Product Citations
publications
BL37-2_PerCPCyanine55_TCRBV1_Antibody_1_041024
Human peripheral blood lymphocytes were stained with CD3 APC and anti-human TCR Vβ1 (clone BL37.2 PerCP/Cyanine5.5 (left) or rat IgG1, κ PerCP/Cyanine5.5 isotype control (right).
  • BL37-2_PerCPCyanine55_TCRBV1_Antibody_1_041024
    Human peripheral blood lymphocytes were stained with CD3 APC and anti-human TCR Vβ1 (clone BL37.2 PerCP/Cyanine5.5 (left) or rat IgG1, κ PerCP/Cyanine5.5 isotype control (right).
See PerCP/Cyanine5.5 spectral data
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360104 100 tests $382
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Description

TCR Vβ1 is a variant of the TCR Vβ chain that is expressed by a subset of αβ+ T cells. Aberrant expression of TCR Vβ chains has been associated with infection and cancer. TCR Vβ1 is reported to be preferably used by autoreactive T cells in a model of autoimmune thyroiditis and diabetes. Skewing of TCR Vβ repertoire to Vβ1 and Vβ9 has also been reported in patients with multiple sclerosis, reactive arthritis, and Kawasaki disease.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Rat cell line RBL-2H3 transfected with human TCR-VB1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Additional Product Notes

BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.

RRID
AB_2562497 (BioLegend Cat. No. 360104)

Antigen Details

Structure
Disulfide-linked 80 kD heterodimer consisting of an α and β chain
Distribution

Subset of αβ+ T cells

Function
Recognize antigens bound to MHC molecules
Ligand/Receptor
Antigen bound MHC molecules
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References

1. Cihak J, et al. 1991. Proc. Natl. Acad. Sci. 88:10951.
2. Wei S, et al. 1994. Immunogenetics. 40:27.
3. Dunon D, et al. 1994. EMBO J. 13:808.

Gene ID
6957 View all products for this Gene ID
UniProt
View information about TCR Vbeta1 on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Go To Top Version: 1    Revision Date: 09/06/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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