PE/Dazzle™ 594 anti-human CD186 (CXCR6) Antibody

Pricing & Availability
K041E5 (See other available formats)
Regulatory Status
Other Names
Mouse IgG2a, κ
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Product Citations
Human peripheral blood lymphocytes were stimulated with IL-2 for 7 days, and then stained with CD3 APC and CD186 (clone K041E5) PE/Dazzle™ 594.
  • K041E5_PEDZL594_CD186_Antibody_FC_070314.jpg
    Human peripheral blood lymphocytes were stimulated with IL-2 for 7 days, and then stained with CD3 APC and CD186 (clone K041E5) PE/Dazzle™ 594.
Compare all formats See PE/Dazzle™ 594 spectral data
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356015 25 tests $159
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356016 100 tests $370
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CD186, also known as CXCR6, is a 39 kD, G-protein coupled chemokine receptor, with seven transmembrane-spanning regions. CXCR6 is expressed on activated and memory T cells. Its ligand is the chemokine CXCL16. CXCR6 is involved in the recruitment of cells to inflamed sites and is also a coreceptor for HIV.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
cDNA encoding human CXCR6
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. Caduff N, et al. 2021. Cell Reports. 35(5):109056. PubMed
  2. Reuschl AK, et al. 2022. Cell Rep. 39:110650. PubMed
AB_2563973 (BioLegend Cat. No. 356015)
AB_2563974 (BioLegend Cat. No. 356016)

Antigen Details

GPCR, seven transmembrane-spanning regions, 39 kD

Memory T cells, activated T cells

Chemotaxis, coreceptor for HIV
Cell Type
T cells
Biology Area
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Kim CH, et al. 2001. J. Clin. Invest. 107:595.
2. Nanki T, et al. 2005. Arthritis Rheum. 52:3004.
3. Van der Voort R, et al. 2005. Arthritis Rheum. 52:1381.
4. Aust G, et al. 2005. Eur. J. Endocrinol. 152:635.
5. Agostini C, et al. 2005. Am. J. Respir. Crit. Care Med. 172:1290.
6. Gaida MM, et al. 2008. Clin. Exp. Immunol. 154:216.
7. Huang Y, et al. 2008. J. Immunol. 180:2367.

Gene ID
10663 View all products for this Gene ID
View information about CD186 on

Related FAQs

Does staining at room temperature or even at 37°C help for checking chemokine receptors expression?

Due to continuous recycling of many chemokine receptors, it may be worthwhile to consider staining at room temperature or at 37°C if the staining at lower temperature (which can potentially reduce receptor turnover) is not optimal.

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For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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  • PE/Cyanine7 anti-human CD186 (CXCR6)

  • Brilliant Violet 421™ anti-human CD186 (CXCR6)

  • PE/Dazzle™ 594 anti-human CD186 (CXCR6)

  • Biotin anti-human CD186 (CXCR6)

  • FITC anti-human CD186 (CXCR6)

  • TotalSeq™-A0804 anti-human CD186 (CXCR6)

  • TotalSeq™-C0804 anti-human CD186 (CXCR6)


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