PE/Cyanine7 anti-mouse CD41 Antibody

Pricing & Availability
MWReg30 (See other available formats)
Regulatory Status
Other Names
Fibrinogen receptor, gpIIb/IIIa, integrin alpha IIb, CD41a
Rat IgG1, κ
Ave. Rating
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Product Citations
Mouse platelets were stained with anti-mouse CD41 (clone MWReg30) PE/Cyanine7 (filled histogram) or rat IgG1 PE/Cyanine7 isotype control (open histogram).
  • MWREG30_PECy7_010912
    Mouse platelets were stained with anti-mouse CD41 (clone MWReg30) PE/Cyanine7 (filled histogram) or rat IgG1 PE/Cyanine7 isotype control (open histogram).
Compare all formats See PE/Cyanine7 spectral data
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133915 25 µg $89
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133916 100 µg $311
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CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
Mouse platelets
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume.  It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: depletion of platelets and functional assay in vivo.4,7 The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for in vivo studies (Cat. No. 133939).

Additional Product Notes
BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Nieswandt B, et al. 1999. Blood 94:684.
  2. Teeling JL, et al. 2001. Blood 98:1095.
  3. Bertrand JY, et al. 2005. P. Natl. Acad. Sci. USA 102:134.
  4. Nocito A, et al. 2007. Hepatology 45:369. (Deplete)
  5. Sullivan BP, et al. 2010. Toxicol. Sci. 115:286. (Deplete) PubMed
  6. van der Heyde HC, et al. 2005. Blood 105:1956. (FA)
  7. Marjon KD, et al. 2009. J. Immunol. 182:1397. (Deplete)
Product Citations
  1. Yamaguchi A, et al. 2021. Genes Cells. 26:782. PubMed
  2. Fujii T, et al. 2015. Proc Natl Acad Sci U S A. 112: 12800 - 12805. PubMed
  3. Lutzmann M, et al. 2019. Cell Rep. 28:2851. PubMed
  4. van Erp EA, et al. 2019. Viruses. 0.811111111. PubMed
  5. Patenaude J, Perreault C 2016. J Immunol. 196: 4760 - 4770. PubMed
  6. Li D, et al. 2021. Mol Med Rep. 23:. PubMed
  7. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  8. Scialdone A, et al. 2016. Nature. 535:289-293. PubMed
  9. Gentek R, et al. 2018. Immunity. 48:1160. PubMed
  10. Brait VH, et al. 2019. Circ Res. 124:279. PubMed
  11. Spevak CC, et al. 2020. Cell Stem Cell. 26(5):755-765. PubMed
  12. Nakagawa MM, et al. 2018. Cell Rep. 25:2094. PubMed
AB_11125173 (BioLegend Cat. No. 133915)
AB_11124102 (BioLegend Cat. No. 133916)

Antigen Details

A transmembrane glycoprotein that is expressed by platelets and megakaryocytes

Platelets, megakaryocytes, and hematopoietic progenitors

Associate with CD61 (integrin β3) to form a complex which plays a major role in platelet adhesion and aggregation
Fibrinogen, fibronectin, von Willebrand factor, thrombin
Cell Type
Hematopoietic stem and progenitors, Megakaryocytes, Platelets
Biology Area
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Bakewell SJ, et al. 2003. P. Natl. Acad. Sci. USA 100:14205.
2. Phillips DR, et al. 1991. Cell. 65:359.

Gene ID
16399 View all products for this Gene ID
View information about CD41 on

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Go To Top Version: 2    Revision Date: 03/19/2013

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Brilliant Violet 421™ anti-mouse CD41

  • Purified anti-mouse CD41

  • FITC anti-mouse CD41

  • PE anti-mouse CD41

  • Alexa Fluor® 488 anti-mouse CD41

  • APC anti-mouse CD41

  • PE/Cyanine7 anti-mouse CD41

  • PerCP/Cyanine5.5 anti-mouse CD41

  • Brilliant Violet 605™ anti-mouse CD41

  • Brilliant Violet 510™ anti-mouse CD41

  • Purified anti-mouse CD41 (Maxpar® Ready)

  • APC/Cyanine7 anti-mouse CD41

  • Alexa Fluor® 700 anti-mouse CD41

  • Biotin anti-mouse CD41

  • Pacific Blue™ anti-mouse CD41

  • Alexa Fluor® 647 anti-mouse CD41

  • PE/Dazzle™ 594 anti-mouse CD41

  • TotalSeq™-A0443 anti-mouse CD41

  • Ultra-LEAF™ Purified anti-mouse CD41

  • TotalSeq™-B0443 anti-mouse CD41

  • TotalSeq™-C0443 anti-mouse CD41


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