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- Clone
- A17207C (See other available formats)
- Regulatory Status
- RUO
- Other Names
- PD-1 homolog, Dies1, B7-H5
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
C57BL/6 mouse splenocytes were stained with CD8a APC and anti-mouse PD-1H (VISTA) (clone A17207C) (left) PE or rat IgG 2a, κ isotype control (right) PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 159503 | 25 µg | $153 | ||||
| 159504 | 100 µg | $377 | ||||
PD-1H, also known as VISTA, is a 309 aa type I transmembrane protein, composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse VISTA protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
Clone A17207C antibody does not affect the binding of clone MIH63 nor clone MH5A.
- RRID
-
AB_2890722 (BioLegend Cat. No. 159503)
AB_2890722 (BioLegend Cat. No. 159504)
Antigen Details
- Structure
- Type I transmembrane protein, member of the CD28 family
- Distribution
-
Macrophages, dendritic cells, neutrophils, NK cells, naïve and activated T cells
- Function
- Negative regulation of immune response
- Ligand/Receptor
- PSGL-1
- Cell Type
- Dendritic cells, Macrophages, Neutrophils, NK cells, T cells, Tregs
- Biology Area
- Immunology, Inhibitory Molecules
- Molecular Family
- Soluble Receptors
- Antigen References
-
- Flies DB, et al. 2011. J. Immunol. 187:1537.
- Wang Li, et al. 2011. J. Exp Med. 208:577.
- Gene ID
- 74048 View all products for this Gene ID
- UniProt
- View information about PD-1H on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All PD-1H Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-mouse PD-1H (VISTA) | A17207C | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-mouse PD-1H (VISTA)
C57BL/6 mouse splenocytes were stained with CD8a APC and ant...
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