PE anti-mouse CD66a (CEACAM1a) Antibody

Pricing & Availability
MAb-CC1 (See other available formats)
Regulatory Status
Other Names
Mouse IgG1, κ
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Product Citations
Balb/c mouse splenocytes stained with MAb-CC1 PE (lower panel) or mouse IgG1 PE isotype control (upper panel) and CD45R/B220 (RA3-6B2) APC
  • A_Mab-CC1_PE_071009.jpg
    Balb/c mouse splenocytes stained with MAb-CC1 PE (lower panel) or mouse IgG1 PE isotype control (upper panel) and CD45R/B220 (RA3-6B2) APC
  • B_Mab-CC1_PE_071009.jpg
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Cat # Size Price Quantity Check Availability Save
134505 25 µg $110
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134506 100 µg $275
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CD66a, known as CEACAM1a, carcinoembryonic antigen-related cell adhesion molecule 1a, is a glycoprotein of the immunoglobulin superfamily and the carcinoembryonic antigen family. Isoforms expressing either two or four alternatively spliced Ig-like domains in mice have been found in a number of epithelial, endothelial, or hematopoietic tissues. CEACAM1a functions as an intercellular adhesion molecule, an angiogenic factor, and a tumor cell growth inhibitor. It also serves as a signal regulatory protein influencing B cell receptor complex-mediated activation. The mouse and human CEACAM1a proteins are targets of viral or bacterial pathogens, respectively. It was reported that targeted disruption of the CEACAM1a gene resulting in a partial ablation of the protein in mice led to reduced susceptibility to virus infection. The antibody recognizes the N-terminal domain of murine CEACAM1a, it does not recognize murine CEACAM1b, an allele in SJL mice.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
SJL/J mice immunized with deoxycholate extracted proteins from BALB/c intestinal brush border membranes.
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Mab-CC1 clone recognizes the MHV binding domain of CD66a2. Pretreatment of murine fibroblasts with Mab-CC1 prevented binding of MHV-A59 and protected cells from infection with MHV-A592. SJL/J mice are resistant to MHV as they express an alternative allele, clone Mab-CC1 does not react against SJL/J cells2.

Application References

(PubMed link indicates BioLegend citation)
  1. Turner BC, et al. 2004. J. Virol. 78 (10):5486
  2. Williams RK, et al. 1990. J. Virol. 64:3817
  3. Dveksler GS, et al. 1993. Proc. Natl. Acad. Sci. USA. 90:1716
Product Citations
  1. Fukushima K, et al. 2020. Immunity. 52(3):542-556. PubMed
  2. Gu A, et al. 2010. PLoS One. 5:e10067. PubMed
  3. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  4. Hammoud A, et al. 2016. PLoS One. 11: 0146281. PubMed
  5. Kojima T, et al. 2016. Sci Rep. 6:36457. PubMed
AB_1659213 (BioLegend Cat. No. 134505)
AB_2077471 (BioLegend Cat. No. 134506)

Antigen Details

A glycoprotein of the immunoglobulin (Ig) superfamily and the carcinoembryonic antigen family

CEACAM1a is abundantly expressed on B cells, granulocytes, some NK cells, monocytes, DCs, and NK cells. It is found on epithelial and endothelial cells.

CEACAM1a is involved in cell adhesion, tumor growth, and viral infection. It regulates on BCR activation of B lymphocytes.
Cell Type
B cells, Dendritic cells, Endothelial cells, Epithelial cells, Granulocytes, Monocytes, NK cells
Biology Area
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Nakagaki K, et al. 2005. J. Virol. 79(10):6102
2. Greicius G et al. 2003. J. Leukoc. Biol. 74(1):126
3. Hemmila E et al. 2004. J. Virol. 78(18):10156

Gene ID
26365 View all products for this Gene ID
View information about CD66a on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 3    Revision Date: 01/05/2017

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • PE anti-mouse CD66a (CEACAM1a)

  • APC anti-mouse CD66a (CEACAM1a)

  • PE/Cyanine7 anti-mouse CD66a (CEACAM1a)

  • FITC anti-mouse CD66a (CEACAM1a)

  • PerCP/Cyanine5.5 anti-mouse CD66a (CEACAM1a)

  • Alexa Fluor® 594 anti-mouse CD66a (CEACAM1a)

  • Alexa Fluor® 488 anti-mouse CD66a (CEACAM1a)

  • Alexa Fluor® 647 anti-mouse CD66a (CEACAM1a)

  • Purified anti-mouse CD66a (CEACAM1a)

  • Brilliant Violet 421™ anti-mouse CD66a (CEACAM1a)

  • Brilliant Violet 650™ anti-mouse CD66a (CEACAM1a)

  • Ultra-LEAF™ Purified anti-mouse CD66a (CEACAM1a)

  • APC/Cyanine7 anti-mouse CD66a (CEACAM1a)


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