- SA045E1 (See other available formats)
- Other Names
- IL-8RB, GRO/MGSA, Cmkar2
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
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CD182, also known as CXCR2, is a G-protein coupled receptor with seven transmembrane regions that is involved in chemotaxis, neutrophil activation, and angiogenesis. CXCR2 is expressed by neutrophils, basophils, a subset of T cells, monocytes, macrophages, natural killer (NK) and natural killer T cells (NKT). Its ligands are CXCL1, CXCL2, CXCL3, and CXCL5.Product Details
- Antibody Type
- Host Species
- Mouse CXCR2-transfected cells.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
AB_2565689 (BioLegend Cat. No. 149609)
AB_2565690 (BioLegend Cat. No. 149610)
- G-protein coupled receptor and seven transmembrane regions.
Neutrophils, basophils, subset of T cells, monocytes, macrophages, and natural killer (NK) cells.
- Chemotaxis, neutrophil activation, and angiogenesis.
- CXCL1, CXCL2, CXCL3, and CXCL5.
- Cell Type
- Basophils, Macrophages, Monocytes, Neutrophils, NK cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
1. Spaan AN, et al. 2014. Nat. Commun. 5:5438.
2. Natsuaki Y, et al. 2014. Nat. Immunol. 15:1064.
3. Hsieh CY, et al. 2014. J. Immunol. 193:3693.
4. Diana J and Lehuen A. 2014. EMBO Mol. Med. 6:1090.
5. Stoolman JS, et al. 2014. J. Immunol. 193:564.
- Gene ID
- 12765 View all products for this Gene ID
- View information about CD182 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
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