- MQ155 (See other available formats)
- Regulatory Status
- Other Names
- Mucin-17, MUC3, MUC-3
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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It is a 451 KD glycocylated member of the mucin family with 2 EGF like domains on the C-terminus and serine/tyrosine phosphorylation sites on the cytoplasmic domain. It is expressed by epithelial cells and plays a role in cytoprotection, signal transduction. Expression of this molecule can also render tumor cells to become less adhesive. It interacts with PKDZ1 and increased expression of this molecule has been reported in colon cancer.Product Details
- Antibody Type
- Host Species
- Purified recombinant Muc17 protein, Freund’s Complete Adjuvant
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
AB_2814359 (BioLegend Cat. No. 395303)
AB_2814360 (BioLegend Cat. No. 395304)
- 451 KD N-glycosylate single pass membrane protein
- Cytoprotection, extravasation, signal transduction
- Biology Area
- Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity
- Antigen References
- Malmberg EK, et al. 2008. Biochem J. 410:283.
- Gum JR Jr, et al. 2002. Biochem Biophys Res Commun. 291:466.
- Hirono S, et al. 2010. Cancer Sci. 101:259.
- Gene ID
- 140453 View all products for this Gene ID
- View information about MUC-17 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
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