PE anti-human CD55 Antibody

Pricing & Availability
JS11 (See other available formats)
VI N-L060
Other Names
DAF (Decay Accelerating Factor)
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes stained with JS11 PE, then detected with anti-mouse IgG FITC
  • JS11
    Human peripheral blood lymphocytes stained with JS11 PE, then detected with anti-mouse IgG FITC
See PE spectral data View Moxi Flow Data
Cat # Size Price Quantity Avail. Save
311308 100 tests $220
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CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.

Product Details
Technical data sheet

Product Details

Human, African Green, Baboon, Cynomolgus
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Peyron P, et al. 2000. J. Immunol. 165:5186
Product Citations
  1. DeZern A, et al. 2014. Exp Hematol. 42:857. PubMed
Publication Library
AB_314865 (BioLegend Cat. No. 311308)

Antigen Details

GPI-achored regulator of complement activation (RCA), type I membrane glycoprotein, 60-70 kD

Hematopoietic cells including erythrocytes and many non-hematopoietic cells

Protects against inappropriate complement activation and cell damage, induces signal transduction, reduces the efficiency of NK cell lysis
C3b, C4b, CD97, Coxsackie viruses
Biology Area
Cell Biology, Immunology, Neuroinflammation, Neuroscience, Costimulatory Molecules
Molecular Family
CD Molecules
Antigen References

1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
2. Hamann J, et al. 1996. J. Exp. Med. 184:1185.
3. Fujita T, et al. 1987. J. Exp. Med. 166:1221

Gene ID
1604 View all products for this Gene ID
View information about CD55 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

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