PE anti-human CD26 Antibody

Pricing & Availability
Clone
BA5b (See other available formats)
Regulatory Status
RUO
Workshop
VI N-L078
Other Names
ADA-binding protein, DPP IV ectoenzyme, EC 3.4.14.5
Isotype
Mouse IgG2a, κ
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Product Citations
publications
BA5b_PE_062107
Human peripheral blood lymphocytes stained with BA5b PE
  • BA5b_PE_062107
    Human peripheral blood lymphocytes stained with BA5b PE
Compare all formats See PE spectral data
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302705 25 tests $110
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302706 100 tests $244
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Description

CD26 is a 110 kD type II membrane protein also known as ADA-binding protein and dipeptidyl peptidase IV (DPPIV). It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides. It plays an integral role as a costimulatory molecule in T cell activation. CD26 may interact with extracellular matrix proteins such as fibronectin or collagen, CD45 and ADA.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Press. London.
  2. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
  1. Cadosch D, et al. 2010. Injury. 41:4. PubMed
  2. Jacob A, et al. 2020. Nature Protocols. 14(12):3303-3332.. PubMed
  3. Scheuplein V, et al. 2015. J Virol. 89:3859. PubMed
  4. Alysandratos KD, et al. 2021. Cell Reports. 36(9):109636. PubMed
  5. Arda HE et al. 2018. Cell systems. 7(3):310-322 . PubMed
  6. Kohli A, et al. 2022. Life Sci Alliance. 5:. PubMed
  7. Berical A, et al. 2022. Nat Commun. 13:4270. PubMed
  8. McCauley KB, et al. 2018. Curr Protoc Stem Cell Biol. 45:e51. PubMed
  9. Hirai H, et al. 2022. Mol Ther Methods Clin Dev. 24:11. PubMed
  10. Worthen CA, et al. 2020. J Invest Dermatol. 140:2515. PubMed
  11. Wang S, et al. 2010. Nephrol Dial Transplant. 26:2144. PubMed
  12. Suzuki S, et al. 2021. STAR Protocols. 2(3):100683. PubMed
  13. Huang J, et al. 2020. Cell Stem Cell. 27(6):962-973.e7. PubMed
  14. Mithal A, et al. 2020. Nat Commun. 0.607638889. PubMed
  15. Spitalieri P, et al. 2022. Cells. 11:. PubMed
  16. Hawkins FJ, et al. 2020. Cell Stem Cell. 28(1):79-95.e8. PubMed
  17. O'Connor MH, et al. 2021. Commun Biol. 4:563. PubMed
  18. Yoon YJ, et al. 2022. Nat Commun. 13:3291. PubMed
  19. Jacob A, et al. 2017. Cell Stem Cell. 1.202777778. PubMed
RRID
AB_314289 (BioLegend Cat. No. 302705)
AB_314290 (BioLegend Cat. No. 302706)

Antigen Details

Structure
Peptidases and ectoenzyme families, type II glycoprotein, 110 kD
Distribution

Thymocyte subset, memory T cells, B cells, NK cells, epithelial cells, macrophages

Function
Dipeptidyl peptidase, T cell costimulation, HIV entry
Ligand/Receptor
Adenosine-deaminase, collagen
Cell Type
B cells, Epithelial cells, Macrophages, NK cells, T cells, Thymocytes
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Kameoka J, et al. 1993. Science 261:466.
2. Dang N, et al. 1990. J. Exp. Med. 172:649.

Gene ID
1803 View all products for this Gene ID
UniProt
View information about CD26 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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