PE anti-human CD200R Antibody

Pricing & Availability
Clone
OX-108 (See other available formats)
Regulatory Status
RUO
Other Names
CD200R1, MOX2R, Orexin Receptor 2 (OX2R), CD200 Receptor
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
OX-108_PE_092308.jpg
Human peripheral blood lymphocytes stained with CD3 (UCHT1) APC and OX-108 PE
  • OX-108_PE_092308.jpg
    Human peripheral blood lymphocytes stained with CD3 (UCHT1) APC and OX-108 PE
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329305 25 tests $122
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329306 100 tests $268
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Description

CD200R, also known as OX2R, is a membrane glycoprotein with up to 70% of its weight derived from N-linked glycosylation. CD200R is expressed primarily by monocytes and neutrophils, but also by other leukocytes including T cells and mast cells. The interaction between CD200 and CD200R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissues.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Reported Reactivity
Baboon
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human CD200R full length fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Wright GJ, et al. 2003. J. Immunol. 171:3034.
Product Citations
  1. Redka DS, et al. 2018. Mol Biol Cell. 29:53. PubMed
  2. Warren K, et al. 2016. J Biol Chem. 291: 24922 - 24930. PubMed
  3. Byrareddy S, et al. 2015. PLoS One. 10: e0140689. PubMed
  4. Najar M, et al. 2012. Immunol Lett. 146:50. PubMed
RRID
AB_2074201 (BioLegend Cat. No. 329305)
AB_2074200 (BioLegend Cat. No. 329306)

Antigen Details

Structure
Immunoglobulin superfamily glycoprotein.
Distribution

Monocytes, neutrophils, T cells, mast cells.

Ligand/Receptor
CD200, OX2.
Cell Type
Mast cells, Monocytes, Neutrophils, T cells
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules
Antigen References

1. Wright GJ, et al. 2003. J. Immunol. 171:3034.
2. Gorczynski R, et al. 2004. J. Immunol. 172:7744.

Gene ID
131450 View all products for this Gene ID
UniProt
View information about CD200R on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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