HRP anti-SOX-10 Antibody

Pricing & Availability
Clone
BSB-62 (See other available formats)
Other Names
Transcription factor SOX-10
Isotype
Mouse IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
BSB-62_HRP_SOX-10_Antibody_1_082718
IHC staining of HRP anti-SOX-10 antibody (clone BSB-62) on formalin-fixed paraffin-embedded mouse brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R (Cat. No. 928602), the tissue was incubated with 5 µg/mL of the primary antibody overnight at 4°C. DAB was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar: 50 µm
  • BSB-62_HRP_SOX-10_Antibody_1_082718
    IHC staining of HRP anti-SOX-10 antibody (clone BSB-62) on formalin-fixed paraffin-embedded mouse brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R (Cat. No. 928602), the tissue was incubated with 5 µg/mL of the primary antibody overnight at 4°C. DAB was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar: 50 µm
  • BSB-62_HRP_SOX-10_Antibody_2_082718
    IHC staining of HRP anti-SOX-10 antibody (clone BSB-62) on formalin-fixed paraffin-embedded rat brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R (Cat. No. 928602), the tissue was incubated with 5 µg/mL of the primary antibody overnight at 4°C. DAB was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar: 50 µm
Cat # Size Price Quantity Avail. Save
847203 25 µg $135
Check Availability


Need larger quantities of this item?
Request Bulk Quote
847204 100 µg $295
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

SOX-10 is a transcriptional activator that is involved in the regulation of embryonic development and in the determination of cell fate.

Product Details
Technical data sheet

Product Details

Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Synthetic peptide corresponding to the N-terminus of human SOX-10.
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 2.0 - 5.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody may show weaker reactivity to human tissues.

RRID
AB_2750297 (BioLegend Cat. No. 847203)
AB_2750298 (BioLegend Cat. No. 847204)

Antigen Details

Structure
SOX-10 is a 466 amino acid protein with a molecular mass of 50 kD.
Distribution

Tissue distribution: primarily expressed in the nuclei of glia in fetal and adult brain, and in the heart, salivary gland and skin.
Cellular distribution: nucleus.

Function
SOX-10 likely functions synergistically with the POU domain protein TST-1/OCT6/SCIP to confer function of other transcription factors in developing and mature glia. The protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development.
Interaction
DNA, PAX3, NMI.
Cell Type
Microglia
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers
Molecular Family
Endosomal Markers
Antigen References

1. Bondurand N, Sham MH. 2013. Dev. Biol. 382(1):330. PubMed
2. Mollaaghababa R, Pavan WJ. 2003. Oncogene. 22(20):3024. PubMed

Gene ID
6663 View all products for this Gene ID
UniProt
View information about SOX-10 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 08/27/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Login/Register
Forgot your password? Reset Password
Request an Account