HRP anti-PSD-93 (Chapsyn-110) Antibody

Pricing & Availability
Clone
N18/28 (See other available formats)
Other Names
Disks large homolog 2, chapsyn-110, discs large homolog 2, synaptic density protein PSD-93, postsynaptic density protein PSD-93, channel-associated protein of synapse-110, PSD93
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
N18-28_HRP_PSD-39_Antibody_022619
Western blot of HRP anti-PSD-93 (Chapsyn-110) antibody (clone N18/28). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain membrane lysate; Lane 3: 20 µg of mouse brain membrane lysate; Lane 4: 20 µg of rat brain membrane lysate. The blot was incubated with 0.5 µg/mL of the primary antibody overnight at 4°C. Enhanced chemiluminescence was used as the detection system (Cat. No. 426303).
  • N18-28_HRP_PSD-39_Antibody_022619
    Western blot of HRP anti-PSD-93 (Chapsyn-110) antibody (clone N18/28). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain membrane lysate; Lane 3: 20 µg of mouse brain membrane lysate; Lane 4: 20 µg of rat brain membrane lysate. The blot was incubated with 0.5 µg/mL of the primary antibody overnight at 4°C. Enhanced chemiluminescence was used as the detection system (Cat. No. 426303).
Cat # Size Price Quantity Avail. Save
818303 25 µg $100
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818304 100 µg $170
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Description

PSD-93, also known as DLG2 or Chapsyn-110, is a member of the MAGUK family important in the scaffolding of receptors with adhesion molecules on the postsynaptic membrane.  It regulates surface expression of receptors by directly interacting with the cytoplasmic tail of NMDA receptor subunits and inward rectifying potassium channels, and is involved in the regulation of synaptic stability at synapses.

Product Details
Technical data sheet

Product Details

Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This monoclonal antibody was raised against a full-length fusion protein (amino acids 1-852) of rat Chapsyn-110 protein.
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody is less reactive in human.

The antibody does not cross-react wtih SAP97, SAP102, or PSD-95.

RRID
AB_2801156 (BioLegend Cat. No. 818303)
AB_2801157 (BioLegend Cat. No. 818304)

Antigen Details

Structure
Expected MW: 110 kD
Cell Type
Neurons
Biology Area
Cell Biology, Neuroscience, Synaptic Biology
Molecular Family
Cytoskeletal Proteins, Postsynaptic proteins, Scaffold Proteins
Gene ID
64053 View all products for this Gene ID
UniProt
View information about PSD-93 (Chapsyn-110) on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 02/26/2019

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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