FITC anti-human CD45RA

Pricing & Availability

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Clone
HI100
Workshop
IV N906
Isotype
Mouse IgG2b, κ
HI100_FITC_CD45RA_ASR_011117
Typical results from human peripheral blood lymphocytes stained either with HI100 FITC used at 5 µL/test (solid line) or with an isotype control (dotted line).
  • HI100_FITC_CD45RA_ASR_011117
    Typical results from human peripheral blood lymphocytes stained either with HI100 FITC used at 5 µL/test (solid line) or with an isotype control (dotted line).
See FITC spectral data
Cat # Size Price Quantity Avail. Save
983002 500 µL $200
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Description

CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Product Details
Technical data sheet

Product Details

Reactivity
Human, Cross-Reactivity: Chimpanzee
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
200 µg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

Suggested for Flow Cytometry

Disclaimer

Precautions for Use: Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.

Antigen Details

Antigen References

1. Thomas M. 1989. Annu. Rev. Immunol. 7:339. 
2. Trowbridge I, et al. 1994. Annu. Rev. Immunol.12:85.

Go To Top Version: 3    Revision Date: 02/06/2018

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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