FITC anti-human CD41b Antibody

Pricing & Availability
Clone
HIP2 (See other available formats)
Workshop
HCDM listed
Other Names
ITGA2B, Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, CD41
Isotype
Mouse IgG3, κ
Ave. Rating
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Product Citations
publications
HIP2_FITC_060812
Human peripheral blood platelets stained with CD41b (clone HIP2) FITC (filled histogram) or anti-mouse IgG3 FITC isotype control.
  • HIP2_FITC_060812
    Human peripheral blood platelets stained with CD41b (clone HIP2) FITC (filled histogram) or anti-mouse IgG3 FITC isotype control.
See FITC spectral data
Cat # Size Price Quantity Avail. Save
354804 100 tests $225
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Description

CD41b is a β chain of glycoprotein IIb (known as CD41) which is associated with glycoprotein IIIa (or integrin β3, CD61) and forms CD41/CD61 complex. CD41/CD61 mediates platelet adhesion and aggregation through the interaction with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is expressed by platelets and megakaryocytes.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Leong L, et al. 1995. J. Cell. Sci. 108:3817.
RRID
AB_11219382 (BioLegend Cat. No. 354804)

Antigen Details

Structure
A β chain of glycoprotein IIb that associates with glycoprotein IIIa to form a CD41/CD61 complex
Distribution

Platelets, Megakaryocytes

Function
Platelet activation and aggregation
Cell Type
Platelets, Megakaryocytes
Biology Area
Angiogenesis, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules, Protein Kinases/Phosphatase
Antigen References

1. Nakahata T, et al. 1994 Leuk. Lymphoma 13:401.

Gene ID
3674 View all products for this Gene ID
UniProt
View information about CD41b on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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