APC anti-mouse CD196 (CCR6) Antibody

Pricing & Availability
29-2L17 (See other available formats)
Regulatory Status
Other Names
CD196, BN-1, CKR-L3, DRY6, KY411, STRL22
Armenian Hamster IgG
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Product Citations
C57BL/6 splenocytes stained with 29-2L17 APC and CD45R/B220 (RA3-6B2) PE
  • A_29-2L17_APC_091809
    C57BL/6 splenocytes stained with 29-2L17 APC and CD45R/B220 (RA3-6B2) PE
  • B_29-2L17_APC_091809
    C57BL/6 splenocytes stained with Armenian Hamster IgG isotype control APC and CD45R/B220 (RA3-6B2) PE
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129813 25 µg $142
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129814 100 µg $350
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CCR6 is a G-protein linked chemokine receptor which binds the chemokine CCL20/MIP-3a. It is expressed on B lymphocytes and certain subsets of dendritic cells and T cells. CCR6 is reported to be involved in mucosal immune response and lymphocyte migration and homeostasis.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
Armenian Hamster
N-terminal peptide (aa. 2-38) of mouse CCR6 fused with GST
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Product Citations
  1. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  2. Liu J, et al. 2011. PLoS One. 6:e19495. PubMed
  3. Sundling C, et al. 2021. Immunity. 54(5):988-1001.e5. PubMed
  4. Yan J, et al. 2020. Cell Rep. 107820:31. PubMed
  5. DiToro D, et al. 2020. Immunity. 650:52. PubMed
  6. Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed
  7. Suan D et al. 2017. Immunity. 47(6):1142-1153 . PubMed
  8. Ulaganathan VK, et al. 2020. Sci Rep. 10:8453. PubMed
  9. Mony J, et al. 2014. Mult Scler. . PubMed
  10. Zhong C, et al. 2020. Immunity. 52(1):83-95.e4.. PubMed
  11. Walker JA, et al. 2020. Immunity. 51(1):104-118. PubMed
AB_1877148 (BioLegend Cat. No. 129813)
AB_1877147 (BioLegend Cat. No. 129814)

Antigen Details

G-protein linked, seven transmembrane, domain-spanning chemokine receptor; 367 amino acids long and about 75% homology with human CCR6

Expressed on spleen B cells, immature splenic dendritic cells in Peyer's patches, and some T cell subset

Important in regulating mucosal immune response
Cell Type
B cells, Dendritic cells, T cells
Biology Area
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Rossi D, et al. 1997. J. Immunol. 158:1033.
2. Lukacs N, et al. 2001. J. Exp. Med. 194:551.
3. Cook DN, et al. 2000. Immunity 12:495

Gene ID
12458 View all products for this Gene ID
View information about CD196 on UniProt.org

Related FAQs

Does staining at room temperature or even at 37°C help for checking chemokine receptors expression?

Due to continuous recycling of many chemokine receptors, it may be worthwhile to consider staining at room temperature or at 37°C if the staining at lower temperature (which can potentially reduce receptor turnover) is not optimal.

Go To Top Version: 1    Revision Date: 11/30/2012

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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  • PE/Fire™ 640 anti-mouse CD196 (CCR6)

  • PE/Fire™ 810 anti-mouse CD196 (CCR6)


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