APC anti-mouse CD117 (c-kit) Antibody

Pricing & Availability
S18020A (See other available formats)
Regulatory Status
Other Names
SCO1, SOW3, CD117, Tr-kitm, Gsfsco5, c-kit
Rat IgG1, κ
Ave. Rating
Submit a Review
Product Citations
C57BL/6 mouse bone marrow cells were stained with anti-mouse CD11b Pacific Blue™ and anti-mouse CD117 (c-kit) (clone S18020A) APC (left) or rat IgG1, κ APC isotype control (right). Data shown were gated on total cell population.
  • S18020A_APC_CD117_Antibody_030222
    C57BL/6 mouse bone marrow cells were stained with anti-mouse CD11b Pacific Blue™ and anti-mouse CD117 (c-kit) (clone S18020A) APC (left) or rat IgG1, κ APC isotype control (right). Data shown were gated on total cell population.
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
161505 25 µg $78
Check Availability

Need larger quantities of this item?
Request Bulk Quote

CD117 is a 145 kD immunoglobulin superfamily member also known as c-kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
Mouse c-kit transfectants
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

S18020A has been tested to block the ligand binding of SCF on c-Kit which is determined by the phosphorylation of ERK1/2 in c-Kit signaling.

AB_2922496 (BioLegend Cat. No. 161505)

Antigen Details

A 145 kD immunoglobulin superfamily member

Hematopoietic stem cells, mast cells, and some acute myeloid leukemia cells

The development of hepatopoietic stem cells
Steel factor, stem cell factor, and mast cell growth factor
Cell Type
Hematopoietic stem and progenitors, Mast cells
Antigen References
  1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook (2nd ed.).  Academic Press.
  2. Galli SJ, et al. 1994. Adv Immunol. 55:1-96.
  3. Ikuta K, et al. 1992. Annu Rev Immunol. 10:759-83.
  4. Besmer P, et al. 1986. Nature. 320:415.
  5. Witte ON. 1990. Cell. 63:5-6.
Gene ID
16590 View all products for this Gene ID
View information about CD117 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 02/28/2022

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-mouse CD117 (c-kit)

  • PE anti-mouse CD117 (c-kit)

  • APC anti-mouse CD117 (c-kit)


Remember me
Forgot your password? Reset Password
Request an Account