APC anti-human IFN-γ, IFN-gamma, 4S.B3

Pricing & Availability

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Clone: 4S.B3
Other Names: Interferon-γ, Immune interferon, Type II interferon, T cell interferon, Macrophage-activating factor (MAF), IFN-g, IFN-gamma
Isotype: Mouse IgG1, κ

4SB3_APC_IFN-gamma_ASR_020323 — Typical result of PMA + Ionomycin with Brefeldin A stimulated (4-hour) human peripheral blood lymphocytes fixed with Fixation Buffer (Cat# 420801), permeabilized with Permeabilization Wash Buffer (Cat# 421002), and intracellularly stained either with 4S.B3 APC used at 5 µL/test (filled histogram) or with an isotype control (open histogram).

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Size

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986702

500 µL

$370

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Description

Interferon-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells.

Product Details

Technical data sheet

Product Details

Reactivity

Human

Formulation

Phosphate-buffered solution, pH7.2, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.

Preparation

The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.

Concentration

25 µg/mL

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

Suggested for Intracellular Staining for Flow Cytometry

Disclaimer

WARNINGS AND PRECAUTIONS

Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
Do not use this reagent beyond the expiration date stated on the label.
Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
Avoid prolonged exposure of the reagent or stained cells to light.

Antigen Details

Antigen References

Fitzgerald K, et al. Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego.
De Maeyer E, et al. 1992. Curr Opin Immunol. 4:321-6.
Farrar M, et al. 1993. Annu Rev Immunol. 11:571-611.
Gray P, et al. 1987. Lymphokines. 13:151.

Documentation

Certificate of Analysis

Go To Top Version: 2 Revision Date: 03/06/2023

Analyte Specific Reagent. Analytical and performance characteristic are not established.

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