APC anti-human CD101 (BB27) Antibody

Pricing & Availability
BB27 (See other available formats)
Regulatory Status
V T040
Other Names
V7, P126
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes stained with CD3 (UCHT1) FITC and BB27 APC
  • BB27_APC_071108.jpg
    Human peripheral blood lymphocytes stained with CD3 (UCHT1) FITC and BB27 APC
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331007 25 tests $161
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CD101 is a type I transmembrane glycoprotein, known as V7, and P126. It is a 120 kD homodimer, the member of EWI family within Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs posses higher inhibitory function. The biological function of CD101 is still not clear. But it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Gouttefangeas C, et al. 1994. Int. Immunol. 6:423
  2. Bouloc A, et al. 2000. Histopathology. 36:229
Product Citations
  1. Zhou J, et al. 2020. Oncol Lett. 1.336111111. PubMed
  2. Weisberg SP, et al. 2020. Cell Reports. 29(12):3916-3932.e5.. PubMed
  3. Richert-Spuhler LE, et al. 2021. Cell Reports Medicine. 2(6):100322. PubMed
  4. Evrard M et al. 2018. Immunity. 48(2):364-379 . PubMed
  5. Kwok I, et al. 2020. Immunity. 53(2):303-318.e5. PubMed
AB_2121761 (BioLegend Cat. No. 331007)

Antigen Details

Type I transmembrane glycoprotein, homodimer, Ig superfamily, 120 kD

Monocytes, granulocytes, dendritic cells, T cell subset and activated T cells

Cell Type
Dendritic cells, Granulocytes, Monocytes, T cells
Biology Area
Antigen References

1. Zola H, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication
2. Bagot M, et al. 1997. Tissue Antigen 50:439

Gene ID
9398 View all products for this Gene ID
View information about CD101 on UniProt.org

Related FAQs

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Go To Top Version: 3    Revision Date: 08/17/2022

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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