Login/Register 
United States ($) USD
Austria (€) EUR
Belgium (€) EUR
Finland (€) EUR
France (€) EUR
Germany (€) EUR
Ireland (€) EUR
Japan (¥) JPY
Luxembourg (€) EUR
Netherlands (€) EUR
Switzerland (CHF) CHF
United Kingdom (£) GBP
  |
Characterizing primary cells from patients with Parkinson’s disease is critical for understanding mechanisms of neurodegeneration. The innovation of induced pluripotent stem cells (iPSCs) has opened opportunities to develop novel disease models, since iPSCs allow for the generation of neurons from more accessible cells. Discover BioLegend’s flow cytometry antibodies and other tools that can be used to isolate and profile iPSC-derived neurons.
 |
| Isolate neurons from differentiated iPSCs by FACS or MojoSort™, using antibodies for CD56, CD24, CD15, and CD184. | Confirm the identity of cultured neurons by visualizing expression of FOXA2, MAP2, β3-tubulin, and neurofilaments with ICC. | Analyze neuronal cell health, characterize neuroinflammation with LEGENDplex™, and simultaneously detect mRNA and protein. |
 |
View our online resources for Parkinson’s disease research, including our webinar on the search for Parkinson’s biomarkers, to get inspired with new ideas.
 |
 |
 |
|
Western blot of increasing concentrations of recombinant human DJ-1 with HRP anti-DJ-1 antibody (A16125E) (left), or of GST-tagged recombinant human DJ-1 with anti-GST antibody (4C10) (right). |
DJ-1 (PARK7) is a multi-functional protein associated with mitochondrial function, mitophagy, and male fertility. It acts as an oxidative stress sensor, redox-sensitive chaperone, and protease. Specific mutations of the protein are linked to autosomal recessive, early onset Parkinson’s disease. Utilize our western blot and IHC reagents for exploring DJ-1’s role in neurodegeneration.
 |
 |
 |
Our Rock the Synapse T-Shirt is the perfect apparel for both neuroscientists and immunologists. Get one of these rad T-Shirts when using a promo code on orders over $250 USD, 200 Euro, 200 GBP, or 250 CHF containing any neuroscience product (Cat. No. beginning with 8).
 |
 |
| Manage your email preferences |
Follow Us