Chemokines are small proteins that regulate chemotaxis or the migration of cells. Some chemokines, like CXCL12 and CXCL13, have homeostatic functions and play a role during basal leukocyte trafficking and stem cell development. Inflammatory chemotactic proteins, like CCL2, CXCL10, and XCL1, are upregulated by an inflammatory stimuli and help to recruit immune cells to a site of infection and can function in wound healing. Given their roles, many chemokines are associated with pathophysiology including tumor metastasis, chronic inflammation, and autoimmune disease.

Try one of our chemoattracting-verified, in-house produced recombinant chemokines for your development and disease studies.

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Simultaneously quantify up to 13 chemokines in serum, plasma, cell culture supernatants or other biological fluids with one of our LEGENDplex™ chemokine panels for human, mouse, or NHP samples. Only need to look at a subset of chemokines? Mix and match any panel to only look at the targets you need.

Check out our Video Library to watch step-by-step protocol guides. Watch our latest videos to streamline your immunoprecipitation experiments with an epitope-tagged affinity gel or measure soluble proteins, like cytokines and chemokines, with our sandwich ELISA protocol video.

IP with an Affinity Gel

Sandwich ELISA