Fighting Cancer from Multiple Angles: Exploring RANK-RANKL, and PD-L1 in mouse melanoma models

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Description: This seminar, presented by Miguel Tam, Senior Product Manager, discusses addressing cancer research using multiple techniques and tools. Specifically, he addresses in vitro models for characterizing melanoma RANK-RANKL interactions, such as cell migration, intracellular signaling, and immunofluorescence microscopy. PD-L1 blocking antibodies are also investigated in an in vivo mouse model, subsequently examined by T cell activation, cytokine and chemokine production, tumor specific T cells, and tumor growth.


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