- MH3-2 (See other available formats)
- Regulatory Status
- Other Names
- T cell receptor V beta 5
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
|Cat #||Size||Price||Quantity Check Availability||Save|
Vβ5 T cell receptor (TCR Vβ5) is a variant of the TCR β chain which is heterodimerized with TCR α chain and expressed on a subset of αβ+ T cells. TCR α/β recognizes peptides presented by the MHC molecules and initiates T cell mediated immune responses. Patients with multiple sclerosis present an expansion of Vβ5.2+/5.3+ autoreactive T cells.Product Details
- Human, Cross-Reactivity: Macaque
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
- Product Citations
AB_10643416 (BioLegend Cat. No. 349301)
- Immunoglobulin superfamily, associates with TCR Vα chain and CD3 complex
- Subset of TCR αβ+ T cells
- Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune response
- MHC-peptide complex
- Cell Type
- T cells
- Biology Area
- Immunology, Adaptive Immunity
- Molecular Family
- Antigen References
1. Kuchroo VK, et al. 2002. Annu. Rev. Immunol. 20:101.
2. Venturi V, et al. 2008. Nat. Rev. Immunol. 8:231.
3. Matsumoto Y, et al. 2003. J. Immunol. 170:4846.
4. Killestein J, et al. 2002. Ann. Neurol. 51:467.
- Gene ID
- 6957 View all products for this Gene ID
- View information about TCR V beta5 on UniProt.org
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.