- QA20A34 (See other available formats)
- Regulatory Status
- Other Names
- Rat IgG1, κ
- Ave. Rating
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- Product Citations
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CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography.
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2922599 (BioLegend Cat. No. 376402)
- Ig superfamily, type I transmembrane glycoprotein, 55 kD
T cell subset, majority of thymocytes, monocytes/macrophages
- MHC class II co-receptor, lymphocyte adhesion, thymic differentiation, HIV receptor
- MHC class II molecules, HIV gp120, IL-16
- Cell Type
- Monocytes, NKT cells, T cells
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
- Center D, et al. 1996. Immunol. Today 17:476-81.
- Gaubin M, et al. 1996. Eur. J. Clin. Chem. Clin. Biochem. 34:723-8.
- Gene ID
- 920 View all products for this Gene ID
- View information about CD4 on UniProt.org
|Purified anti-human CD4 Recombinant Antibody||QA20A34||IHC-P|
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