- QA17A55 (See other available formats)
- Regulatory Status
- Other Names
- Common γ chain, γc, IL-2 receptor γ subunit
- Mouse IgG1, κ
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- Product Citations
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CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common γ chain (γc), or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography.
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2892384 (BioLegend Cat. No. 314602)
- Type I transmembrane glycoprotein, Ig superfamily 64-70 kD
T cells, B cells, NK, monocytes, granulocytes
- Component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21
- Antigen References
1. Corrigall V, et al. 2001. J Immunol. 166(6):4141-7.
- Gene ID
- 3561 View all products for this Gene ID
- View information about CD132 on UniProt.org
Related Pages & Pathways
Other FormatsView All CD132 Reagents Request Custom Conjugation
|PE anti-human CD132 (IL-2R g) Recombinant Antibody||QA17A55||FC|
|Purified anti-human CD132 (IL-2R g) Recombinant Antibody||QA17A55||FC|
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