Purified anti-Blood Group Antigen Precursor (BG1) Antibody

Pricing & Availability
Clone
K21 (See other available formats)
Regulatory Status
RUO
Other Names
Blood group antigen precursor, type 1 (BG1)
Isotype
Mouse IgM, κ
Ave. Rating
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Product Citations
publications
K21_PURE_BG1_Antibody_IHC_062415
Staining of BG1 (clone K21) on formalin-fixed paraffin embedded human kidney tumor tissue.
  • K21_PURE_BG1_Antibody_IHC_062415
    Staining of BG1 (clone K21) on formalin-fixed paraffin embedded human kidney tumor tissue.
Cat # Size Price Quantity Avail. Save
932101 25 µg 80€
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932102 100 µg 196€
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Description

BG1 is the precursor molecule for major blood group antigens, including the ABO and Lewis blood groups.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Tera-1 teratocarcinoma cell line.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunohistochemistry. For immunohistochemistry, a concentration range of 0.5 - 5.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Tissue Sections: Formalin-fixed, paraffin-embedded tissues, and frozen tissues.
Pre-treatment: Not required.
Incubation: 20-60 minutes at room temperature.
Positive Control: Human kidney tumor tissue.

Application Notes

Clone K21 is specific for the Lacto-N-tetraose carbohydrate moiety.

We recommend using our Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species) (Cat. No. 929601).

Application References
  1. Bry L, et al. 1996. Proc. Natl. Acad. Sci. USA 93:1161. (IHC)
  2. Domino S, et al. 2001. Mol. Cell Biol. 21:8336. (IHC) PubMed
Product Citations
  1. Domino S, et al. 2001. Mol Cell Biol. 21:8336-8345. PubMed
RRID
AB_2566099 (BioLegend Cat. No. 932101)
AB_2566098 (BioLegend Cat. No. 932102)

Antigen Details

Structure
Lacto-N-tetraose carbohydrate moiety.
Distribution
Widely expressed on red blood cells, epithelial tumors, teratocarcinoma, and renal-cell carcinoma.
Function
BG1 is the substrate for the ABO blood group-related antigens.
Biology Area
Cancer Biomarkers, Cell Biology, Neuroinflammation, Neuroscience
Antigen References

1. Franchini M and Liumbruno GM. 2013. Clin. Chem. Lab. Med. 51(8):1545.

Gene ID
NA
UniProt
View information about BG1 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 07/15/2015

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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