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Purified anti-Blood Group Antigen Precursor (BG1) Antibody

Pricing & Availability
Clone
K21 (See other available formats)
Regulatory Status
RUO
Other Names
Blood group antigen precursor, type 1 (BG1)
Isotype
Mouse IgM, κ
Ave. Rating
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Product Citations
publications
K21_PURE_BG1_Antibody_IHC_062415
Staining of BG1 (clone K21) on formalin-fixed paraffin embedded human kidney tumor tissue.
  • K21_PURE_BG1_Antibody_IHC_062415
    Staining of BG1 (clone K21) on formalin-fixed paraffin embedded human kidney tumor tissue.
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932101 25 µg 95€
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932102 100 µg 231€
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Description

BG1 is the precursor molecule for major blood group antigens, including the ABO and Lewis blood groups.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Tera-1 teratocarcinoma cell line.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunohistochemistry. For immunohistochemistry, a concentration range of 0.5 - 5.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Tissue Sections: Formalin-fixed, paraffin-embedded tissues, and frozen tissues.
Pre-treatment: Not required.
Incubation: 20-60 minutes at room temperature.
Positive Control: Human kidney tumor tissue.

Application Notes

Clone K21 is specific for the Lacto-N-tetraose carbohydrate moiety.

We recommend using our Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species) (Cat. No. 929601).

Application References
  1. Bry L, et al. 1996. Proc. Natl. Acad. Sci. USA 93:1161. (IHC)
  2. Domino S, et al. 2001. Mol. Cell Biol. 21:8336. (IHC) PubMed
Product Citations
  1. Domino S, et al. 2001. Mol Cell Biol. 21:8336-8345. PubMed
RRID
AB_2566099 (BioLegend Cat. No. 932101)
AB_2566098 (BioLegend Cat. No. 932102)

Antigen Details

Structure
Lacto-N-tetraose carbohydrate moiety.
Distribution

Widely expressed on red blood cells, epithelial tumors, teratocarcinoma, and renal-cell carcinoma.

Function
BG1 is the substrate for the ABO blood group-related antigens.
Biology Area
Cancer Biomarkers, Cell Biology, Neuroinflammation, Neuroscience
Antigen References

1. Franchini M and Liumbruno GM. 2013. Clin. Chem. Lab. Med. 51(8):1545.

Gene ID
NA
UniProt
View information about BG1 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 01/05/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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