- F3 (See other available formats)
- Regulatory Status
- Other Names
- Blood Group Related Antigen BG-8
Signet Catalog# 317-01
Covance Catalog# SIG-3317
- Mouse IgM
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- Product Citations
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BG-8 is also known as blood group Lewis Y F3. The Lewis Y (type 2 chain) antigen is found on the Type 2 blood group oligosaccharides of glycolipids and glycoproteins. It has been detected in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors and is being investigated as a diagnostic marker for several forms of cancer.Product Details
- Antibody Type
- Host Species
- This antibody was developed against SK-LU-3 lung cancer cell lines.
- Phosphate-buffered solution with BSA + 0.1% NaN3.
- The antibody was purified by ammonium sulfate precipitation.
- Storage & Handling
- Store between 2°C and 8°C.
- Recommended Usage
Each lot of this antibody is quality control tested by immunohistochemical staining.
The optimal working dilution should be determined for each specific assay condition.
• IHC: ≥1:40 for Biotin based detection systems such as USA Ultra Streptavidin Detection (Cat. No. 929501).
Tissue Sections: Formalin-fixed, paraffin-embedded tissues.
Pretreatment: Not required
Incubation: 20 minutes at room temperature
- Application Notes
This antibody is effective in immunohistochemistry (IHC).
Positive tissue (human): Colon adenocarcinoma
F3 is specific for Lewis Y (Type 2 Chain).
- Application References
- Yaziji H, et al. 2006. Mod Pathol. 19:514.
- Ordonez NG. 2006. Mod Pathol. 19:34.
- Ordonez NG. 2006. Mod Pathol. 19:417.
- Ordonez NG. 2000. Am J Surg Pathol. 24: 598.
- Zhu ZM, et al. 1995. Biol Reprod. 52:903.
- Gaffney RA, et al. 1992. J Urol. 148:1341.
- Jordon D, et al. 1989. Am J Pathol 135:931.
- Product Citations
AB_2565124 (BioLegend Cat. No. 912501)
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