Anti-BG-8 Antibody (Previously Covance catalog# SIG-3317)

Pricing & Availability
Clone
F3 (See other available formats)
Regulatory Status
RUO
Other Names
Blood Group Related Antigen BG-8
Previously
Signet Catalog# 317-01
Covance Catalog# SIG-3317
Isotype
Mouse IgM
Ave. Rating
Submit a Review
Product Citations
publications
Cat # Size Price Quantity Avail. Save
912501 1 mL 274€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

BG-8 is also known as blood group Lewis Y F3. The Lewis Y (type 2 chain) antigen is found on the Type 2 blood group oligosaccharides of glycolipids and glycoproteins. It has been detected in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors and is being investigated as a diagnostic marker for several forms of cancer.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was developed against SK-LU-3 lung cancer cell lines.
Formulation
Phosphate-buffered solution with BSA + 0.1% NaN3.
Preparation
The antibody was purified by ammonium sulfate precipitation.
Storage & Handling
Store between 2°C and 8°C.
Application

IHC

Recommended Usage

Each lot of this antibody is quality control tested by immunohistochemical staining.

The optimal working dilution should be determined for each specific assay condition.
IHC: ≥1:40 for Biotin based detection systems such as USA Ultra Streptavidin Detection (Cat. No. 929501).

Tissue Sections: Formalin-fixed, paraffin-embedded tissues.
Pretreatment: Not required
Incubation: 20 minutes at room temperature

Application Notes

This antibody is effective in immunohistochemistry (IHC).

Positive tissue (human): Colon adenocarcinoma

F3 is specific for Lewis Y (Type 2 Chain).

Application References
  1. Yaziji H, et al. 2006. Mod Pathol. 19:514.
  2. Ordonez NG. 2006. Mod Pathol. 19:34.
  3. Ordonez NG. 2006. Mod Pathol. 19:417.
  4. Ordonez NG. 2000. Am J Surg Pathol. 24: 598.
  5. Zhu ZM, et al. 1995. Biol Reprod. 52:903.
  6. Gaffney RA, et al. 1992. J Urol. 148:1341.
  7. Jordon D, et al. 1989. Am J Pathol 135:931.
Product Citations
  1. Rimkute I, et al. 2020. J Biol Chem. 295:15974. PubMed
RRID
AB_2565124 (BioLegend Cat. No. 912501)

Related FAQs

There are no FAQs for this product.
Go To Top Version: 3    Revision Date: 10/06/2016

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Insert Note Here
Save Close Clear
Lab Timer
Tools
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account