Purified anti-SNAT1 Antibody

Pricing & Availability
Clone
N104/37 (See other available formats)
Other Names
SNAT1, SLC38A1
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
N104-37_Purified_SNAT1_1_112018
Western blot of purified anti-SNAT1 antibody (clone N104/37). Lane 1: Molecular weight marker; Lane 2: 40 µg of human brain lysate; Lane 3: 20 µg of mouse brain lysate. The blot was incubated with 10 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP-labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
  • N104-37_Purified_SNAT1_1_112018
    Western blot of purified anti-SNAT1 antibody (clone N104/37). Lane 1: Molecular weight marker; Lane 2: 40 µg of human brain lysate; Lane 3: 20 µg of mouse brain lysate. The blot was incubated with 10 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP-labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
Cat # Size Price Quantity Avail. Save
857801 25 µg £47
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857802 100 µg £94
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Description

SNAT1, also called sodium-coupled neutral amino acid transporter 1, plays an essential role in glutamine uptake and neurotransmitter recycling. SNAT1 has been shown to mediate the co-transport of glutamine and sodium ions in a pH-sensitive manner, and contributes to the replenishment of neurotransmitters glutamate and GABA.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5.0 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Brown MN, et al. 2010. J Neurochem. 114(3):909 (WB)
RRID
AB_2783479 (BioLegend Cat. No. 857801)
AB_2783480 (BioLegend Cat. No. 857802)

Antigen Details

Structure
SNAT1 is a 485 amino acid protein with an apparent molecular mass of ~ 54 kD.
Distribution

Tissue Distribution: Brain, Lung, endocrine tissue, and small intestine.
Cellular Distribution: Extracellular and plasma membrane.

Function
SNAT1 mediates the co-transport of extracellular glutamine and sodium ions to the cytosol.
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers, Synaptic Biology, Transcription Factors
Antigen References
  1. Schioth HB, et al. 2013. Mol Aspects Med. 34(2-3):571
  2. Mackenzie B, et al. 2004. Pflugers Arch. 447(5):784
  3. Conti F, et al. 2006. Neurochem Int. 48(6-7):459
Gene ID
105727 View all products for this Gene ID
UniProt
View information about SNAT1 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/21/2018

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