Purified anti-rat CD5 Antibody

Pricing & Availability
Clone
OX-19 (See other available formats)
Other Names
Ly-1, Tp67, Leu-1, T1, Lyt-1
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
OX-19_Pure_061708.jpg
LOU rat splenocytes stained with OX-19 purified, followed by anti-mouse IgG PE
  • OX-19_Pure_061708.jpg
    LOU rat splenocytes stained with OX-19 purified, followed by anti-mouse IgG PE
Cat # Size Price Quantity Avail. Save
203501 100 µg £72
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Description

CD5 is a 67 kD glycoprotein, also known as Lyt-1, Ly-1 or Ly-12. It is a member of the scavenger receptor superfamily and primarily expressed on thymocytes and mature peripheral T lymphocytes, but not on NK cells, intestinal intraepithelial gamma/delta T cells. A CD5+ B cell subset (B-1) has not been characterized in that rat.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Rat thymocyte lentil lectin-binding glycoproteins
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
ICC - Reported in the literature

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Dallman MJ, et al. 1984. Eur. J. Immunol. 14:260.
  2. Vemeer LA, et al. 1994. Eur. J. Immunol. 24:585.
RRID
AB_1089042 (BioLegend Cat. No. 203501)

Antigen Details

Structure
CD5 is a 67 kD glycoprotein of scavenger receptor superfamily. It is expressed on thymocytes, T cells and small subset of B cells.
Distribution

Expressed on thymocytes, peripheral T cells, and some thymic dendritic cells. It should be noted that a CD5+ subset of B cells has not been characterized in the rat by OX-19. Most gamma/delta T cells do not express CD5.

Function
Important in T-B cell interaction.
Ligand/Receptor
CD72
Biology Area
Immunology, Costimulatory Molecules
Molecular Family
CD Molecules, TCRs
Antigen References

1. Vermeer LA, et al. 1994. Eur. J. Immunol. 24:585.

Gene ID
54236 View all products for this Gene ID
UniProt
View information about CD5 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

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