Purified anti-mouse Trem-like 4 (Treml4) Antibody

Pricing & Availability
16E5 (See other available formats)
Regulatory Status
Other Names
Trem-l4, TREM like transcript 4, triggering receptor expressed on myeloid cells-like 4
Rat IgG1, κ
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Product Citations
C57BL/6 mouse splenocytes were stained with Treml4 (clone 16E5) PE (filled histogram) or rat IgG1, κ PE isotype control (open histogram). Data shown was from gated on CD8+CD11c+ cells.
  • 16E5_PE_010412
    C57BL/6 mouse splenocytes were stained with Treml4 (clone 16E5) PE (filled histogram) or rat IgG1, κ PE isotype control (open histogram). Data shown was from gated on CD8+CD11c+ cells.
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143302 100 µg £157
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Trem-like 4, a type I transmembrane protein and a member of the TREM family, consists of a single extracellular Ig-like domain of the V-type, a transmembrane domain, and a short cytoplasmic domain. Trem-like 4 is expressed on macrophages in the spleen, and dendritic cells, especially CD8+ dendritic cells. It is proposed to regulate the immune response based on its expression profile. It has been reported that B7-H3 is a receptor and that the soluble form of Treml4 has a binding affinity to late apoptotic or necrotic cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Extracellular domain of recombinant mouse Trem-like 4
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IHC-F, IP, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescent staining, immunoprecipitation, and Western blotting1.

Application References

(PubMed link indicates BioLegend citation)
  1. Hemmi H, et al. 2009. J. Immunol. 182:1278. (WB)
AB_11149169 (BioLegend Cat. No. 143302)

Antigen Details

Type I transmembrane protein; member of the TREM family

CD8+ dendritic cells, dendritic cell subsets, macrophages in the spleen, myeloid cells

Regulates innate immune response and homeostatis
Associates with DAP12; binds late apoptotic cells/necrotic cells
Cell Type
B cells, Dendritic cells, Macrophages
Biology Area
Immunology, Innate Immunity
Molecular Family
MHC Antigens
Antigen References

1. Ford JW and McVicar DW. 2009. Curr. Opin. Immunol. 21:38.
2. Hemmi H, et al. 2009. J. Immunol. 182:1278.

Gene ID
224840 View all products for this Gene ID
View information about Trem-like 4 on UniProt.org

Related FAQs

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Go To Top Version: 3    Revision Date: 04/08/2020

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  • Purified anti-mouse Trem-like 4 (Treml4)

  • PE anti-mouse Trem-like 4 (Treml4)


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