Purified anti-mouse TCR Vγ1.1/Cr4 Antibody

Pricing & Availability
2.11 (See other available formats)
Regulatory Status
Other Names
T cell receptor Vgamma 1.1, TCR Vγ1, TCR Cr4
Armenian hamster IgG
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Product Citations
C57BL/6 mouse lymph node cells were stained with anti-mouse TCR γ/δ (clone GL3) APC and anti-mouse TCR Vγ1.1 (clone 2.11) FITC (top) or Armenian hamster IgG FITC isotype control (bottom).
  • 2.11_FITC_1_113010
    C57BL/6 mouse lymph node cells were stained with anti-mouse TCR γ/δ (clone GL3) APC and anti-mouse TCR Vγ1.1 (clone 2.11) FITC (top) or Armenian hamster IgG FITC isotype control (bottom).
  • 2.11_FITC_2_113010
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141102 100 µg £120.00
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T cell receptor (TCR) is a heterodimer consisting of an α and β chain (TCR α/β) or a γ and δ chain (TCR γ/δ). TCR associates with CD3 to form a CD3/TCR complex.  The CD3/TCR plays a key role in antigen recognition, signal transduction, and T cell activation.  TCR Vγ1.1 (Garman nomenclature) is also called TCR Vγ1 (Tonegawa nomenclature). The Vγ1 gene almost exclusively rearranges to the Jγ4-Cγ4 gene. Vγ1- Jγ4-Cγ4 expressing cells constitute a major population of γ/δ T cells in thymus and peripheral lymphoid organs in adult mice, but they are only composed of a minor population of γ/δ T cells during fetal and early postnatal life. Vγ1 T cell development can happen in thymus-dependent and thymus-independent manners. Further studies have shown that the antibody 2.11 recognized epitote is located in Cr4 domain.

Product Details
Technical Data Sheet (pdf)

Product Details

Antibody Type
Host Species
Armenian Hamster
T3.13.1 T-cell hybridoma cell line
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation1.

Application References

(PubMed link indicates BioLegend citation)
  1. Pereira P, et al. 1995. J. Exp. Med. 182:1921. (IP)
  2. Pereira P and Boucontet L. 2004. J. Immunol. 173:3261. (FC)
  3. Pereira P, et al. 1996. Intl. Immunol. 8:83. (FC)
Product Citations
  1. Mensurado S, et al. 2018. PLoS Biol. 16:e2004990. PubMed
AB_10693548 (BioLegend Cat. No. 141102)

Antigen Details

Ig superfamily

Subset of γ/δ T-cells

Antigen recognition
Cell Type
T cells
Biology Area
Immunology, Adaptive Immunity
Molecular Family
Antigen References

1. Pereira P, et al. 1995. J. Exp. Med. 182:1921.
2. Grigoriadou K, et al. 2002. J. Immunol. 169:3736.

Gene ID
110067 View all products for this Gene ID
View information about TCR V gamma1.1 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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