Purified anti-mouse/rat CD161f (NKPR1f) Antibody

Pricing & Availability
Clone
C8 (See other available formats)
Other Names
Killer cell lectin-like receptor subfamily B member 1F (Klrb1f), Nkr-p1f, Nkrp1-f, A630024B12Rik
Isotype
Rat IgG1, κ
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Product Citations
publications
C8_Purified_NKRP1F_Antibody_FC_1_091014.jpg
C57BL/6 splenocytes were stained with NK1.1 APC and purified NKRP1f (clone C8) (top) or rat IgG1, κ istoype control (bottom), followed by anti-rat IgG PE.
  • C8_Purified_NKRP1F_Antibody_FC_1_091014.jpg
    C57BL/6 splenocytes were stained with NK1.1 APC and purified NKRP1f (clone C8) (top) or rat IgG1, κ istoype control (bottom), followed by anti-rat IgG PE.
  • C8_Purified_NKRP1F_Antibody_FC_2_091014
Cat # Size Price Quantity Avail. Save
148902 100 µg £133
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Description

CD161, also known as NKRP1f, is mainly expressed on NK cells with little to no expression on T or B cells. NKRP1f on the surface of dendritic cells can bind to Clr-g expressed on activated T cells and result in production of IL-2 and proliferation of T cells. NKRP1f may also play a role in the formation of synapses between T cells and antigen presenting dendritic cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Mouse, Rat
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
NKRP1f transfected YB2/0 rat plasmacytoma cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2564270 (BioLegend Cat. No. 148902)

Antigen Details

Structure
CLR family, 24.7 kD, ITIM-less activation receptor
Distribution
NK cells, dendritic cells
Function
Facilitates IL-2 production and proliferation of T cells and may contribute to the formation of immunological synapses.
Ligand/Receptor
Clr-g
Cell Type
NK cells, Dendritic cells
Biology Area
Cell Biology, Immunology, Signal Transduction
Molecular Family
CD Molecules
Antigen References

1. Skálová T, et al. 2012. J. Immunol. 189:4881.
2. Tian W, et al. 2005. Cell Immunol. 234:39.
3. Plougastel B, et al. 2001. Immunogenetics. 53:592.
4. Kveberg L, et al. 2011. Immunogenetics. 63:429.

Gene ID
232408 View all products for this Gene ID
UniProt
View information about CD161f on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 09/15/2014

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

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