- C8 (See other available formats)
- Other Names
- Killer cell lectin-like receptor subfamily B member 1F (Klrb1f), Nkr-p1f, Nkrp1-f, A630024B12Rik
- Rat IgG1, κ
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CD161, also known as NKRP1f, is mainly expressed on NK cells with little to no expression on T or B cells. NKRP1f on the surface of dendritic cells can bind to Clr-g expressed on activated T cells and result in production of IL-2 and proliferation of T cells. NKRP1f may also play a role in the formation of synapses between T cells and antigen presenting dendritic cells.Product Details
- Mouse, Rat
- Antibody Type
- Host Species
- NKRP1f transfected YB2/0 rat plasmacytoma cells.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2564270 (BioLegend Cat. No. 148902)
- CLR family, 24.7 kD, ITIM-less activation receptor
- NK cells, dendritic cells
- Facilitates IL-2 production and proliferation of T cells and may contribute to the formation of immunological synapses.
- Cell Type
- NK cells, Dendritic cells
- Biology Area
- Cell Biology, Immunology, Signal Transduction
- Molecular Family
- CD Molecules
- Antigen References
1. Skálová T, et al. 2012. J. Immunol. 189:4881.
2. Tian W, et al. 2005. Cell Immunol. 234:39.
3. Plougastel B, et al. 2001. Immunogenetics. 53:592.
4. Kveberg L, et al. 2011. Immunogenetics. 63:429.
- Gene ID
- 232408 View all products for this Gene ID
- View information about CD161f on UniProt.org
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