Purified anti-MART-1 Antibody anti-MART-1

Pricing & Availability

Clone: M2-7C10 (See other available formats)
Regulatory Status: RUO
Other Names: MLANA, Melanoma antigen recognized by T-cells 1, antigen LB39-AA, antigen SK29-AA, protein Melan-A
Previously: Signet Catalog# 8160-01
Signet Catalog# 8160-26 L2 Predilute
Covance Catalog# SIG-38160
Isotype: Mouse IgG2b, κ
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Product Citations: publications

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917902

6 mL

£297

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Description

Melan-A, also known as melanoma antigen recognized by T cells 1 (MART-1), antigen LB39-AA, and antigen SK29-AA, is an 18 kD transmembrane protein that is expressed in a large proportion of melanomas and melanoma cell lines.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

This antibody was generated against a MART-1 fusion protein.

Formulation

Phosphate-buffered solution with BSA + 0.09% NaN₃.

Previous lots of this product may have been formulated with 0.1% or 0.05% NaN₃ instead of 0.09% NaN₃. For further information please contact BioLegend Technical Support or Customer Service.

Preparation

The antibody was purified by affinity chromatography.

Storage & Handling

Store between 2°C and 8°C.

Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. This antibody is pre-diluted, and is ready-to-use with Biotin-based detection systems such as USA Ultra Streptavidin Detection.

Application Notes

This antibody is effective in immunohistochemistry on formalin-fixed paraffin-embedded tissue (IHC-P).

This antibody recognizes MART-1 (Melan-A) [MART1, MART 1] an 18kD transmembrane protein that is expressed in cells of melanocytic lineage. MART-1 is expressed by a large proportion of melanomas and by melanoma cell lines.

In Immunohistochemistry citrate retrieval has also been verified for use with this clone.

Additional Product Notes

Please note, this product (Cat. No. 917902) is sold in pre-diluted format. For the concentrated format of this product, please see Cat. No. 917901.

Application References (PubMed link indicates BioLegend citation)

Shidham VB, et al. 2001. Am. J. Surg. Pathol. 25:1039.
Fetsch PA, et al. 1999. Cancer Cytopath. 87:37.
Yu LL, et al. 1999. Cancer. 86:617.
Beaty MW, et al. 1997. Cancer (Cancer Cytopathology). 81:57.
Marincola FM, et al. 1996. J. Immunother. Emphasis Tumor Immunol. 19:192.
Rivoltini L, et al. 1995. J. Immunol. 154:2257.
Kawakami Y, et al. 1994. J. Exp. Med. 180:347.
Kawakami Y, et al. 1994. Proc. Natl. Acad, Sci. USA. 91:3515.

Product Citations

Zu T, et al. 2021. Lab Invest. 101:636. PubMed

RRID

AB_2565203 (BioLegend Cat. No. 917902)

Antigen Details

Biology Area: Cell Biology, Immunology, Innate Immunity
Molecular Family: MHC Antigens
Gene ID: 2315 View all products for this Gene ID
UniProt: View information about MART-1 on UniProt.org

Documentation

Reviews

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Related Protocols

Immunohistochemistry Protocol for Paraffin-Embedded Sections

Related Products

Description	Clone	Applications

Related Pages & Pathways

Related FAQs

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Other Formats

View All MART-1 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-MART-1	M2-7C10	IHC-P
Alexa Fluor® 594 anti-MART-1	M2-7C10	IHC-P
Purified anti-MART-1	M2-7C10	IHC-P

Certificate of Analysis

Go To Top Version: 6 Revision Date: 02/08/2024

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

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