- Poly28600 (See other available formats)
- Other Names
- Lysozyme, LZM, 1,4-Beta-N-Acetylmuramidase C, EC 188.8.131.52, Lysozyme C, Lysozyme (Renal Amyloidosis) 2
- Rabbit Polyclonal IgG
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- Product Citations
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Lysozyme is an antimicrobial enzyme that is abundantly present in secretions such as tears, saliva and mucus. Its hydrolase activity leads to the breakdown of the gram-positive bacterial cell wall and lysis of the bacteria.Product Details
- Human, Mouse, Rat
- Antibody Type
- Host Species
- Recombinant Lysozyme expressed in E.coli.
- 0.01 M PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
WB - Quality tested
IHC-P - Validated
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per ml for human, and 1.0 - 2.0 µg per ml for mouse and rat. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 1.0 - 5.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Lysozyme is a 148 amino acid protein with an apparent molecular mass of ~ 16kD.
Tissue Distribution: Spleen, kidney, milk, tears, and plasma
Cellular Distribution: Cytosol
- Lysozyme is expressed in many immune cells including monocytes and macrophages. It plays an important role in innate immunity by hydrolyzing peptidoglycans found in bacterial cell wall and thus destroying the bacteria.
- Bacterial peptidoglycan
- Cell Type
- Macrophages, Mesenchymal cells, Monocytes, Neutrophils
- Biology Area
- Bacterial proteins and Toxins, Cell Biology, Immunology, Innate Immunity
- Molecular Family
- Enzymes and Regulators, Innate Immune Signaling, Proteases
- Antigen References
- Mallamace D, et al. 2018. Int J Mol Sci. 19(12): E3825.
- Delorme-Axford E and Klionsky DJ. 2018. Autophagy. 14(3):365.
- Gene ID
- 4068 View all products for this Gene ID 17110 View all products for this Gene ID 25211 View all products for this Gene ID
- View information about Lysozyme on UniProt.org
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