Purified anti-human TCR Vβ5 Antibody

Pricing & Availability
MH3-2 (See other available formats)
Regulatory Status
Other Names
T cell receptor V beta 5
Mouse IgG2a, κ
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Product Citations
Human peripheral blood lymphocytes stained with purified MH3-2 conjugated with Alexa Fluor® 647 and CD3 PE
  • MH3-2_AF647_072110
    Human peripheral blood lymphocytes stained with purified MH3-2 conjugated with Alexa Fluor® 647 and CD3 PE
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349301 25 µg £68
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Vβ5 T cell receptor (TCR Vβ5) is a variant of the TCR β chain which is heterodimerized with TCR α chain and expressed on a subset of αβ+ T cells. TCR α/β recognizes peptides presented by the MHC molecules and initiates T cell mediated immune responses. Patients with multiple sclerosis present an expansion of Vβ5.2+/5.3+ autoreactive T cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Reported Reactivity
Pigtailed Macaque
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Labrecque N, et al. 1993. J. Exp. Med. 177:1735. (FC)
  2. Oh S, et al. 2004. Cancer Res. 64:2610. (FC)
  3. Wilson JDK, et al. 1998. Eur. J. Immunol. 28:1172. (FC)
  4. Patel MR, et al. 2010. Cancer Res. 70:10141. PubMed
  5. Han JA, et al. 2014. Nanomedicine. 10:561. PubMed
Product Citations
  1. Patel M, et al. 2010. Cancer Res. 70:10141. PubMed
  2. Han J, et al. 2014. Nanomedicine. 10:561. PubMed
AB_10643416 (BioLegend Cat. No. 349301)

Antigen Details

Immunoglobulin superfamily, associates with TCR Vα chain and CD3 complex

Subset of TCR αβ+ T cells

Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune response
MHC-peptide complex
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
Antigen References

1. Kuchroo VK, et al. 2002. Annu. Rev. Immunol. 20:101.
2. Venturi V, et al. 2008. Nat. Rev. Immunol. 8:231.
3. Matsumoto Y, et al. 2003. J. Immunol. 170:4846.
4. Killestein J, et al. 2002. Ann. Neurol. 51:467.

Gene ID
6957 View all products for this Gene ID
View information about TCR V beta5 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 12/14/2021

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-human TCR Vβ5


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