- H131 (See other available formats)
- Regulatory Status
- Other Names
- T cell receptor Vβ13.1 chain, TCRBV13.1, TCRBV13
- Mouse IgG2b, κ
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- Product Citations
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TCR Vβ13.1 is a variant of the TCR β chain. The receptor is complexed with the TCR α chain and belongs to the immunoglobulin superfamily. It is expressed on a subset of T cells and some T cell clones. Variability in the β chain is generated by Vβ, Dβ, and Jβ gene rearrangement, while variability in the α chain is generated by Vα and Jα rearrangement. TCR Vβ13.1 has been shown to be related to antigen recognition and inflammation as well as diseases, such as HIV and multiple sclerosis.Product Details
- Antibody Type
- Host Species
- Mouse T cell hybridoma
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
Activ - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats of this clone) include: activation of TCR Vß13.1 expressing cells1.
(PubMed link indicates BioLegend citation)
- Choi YW, et al. 1991. Proc. Natl. Acad. Sci. USA 88:8357.
AB_2563503 (BioLegend Cat. No. 362402)
- Immunoglobulin superfamily
Subset of T cells
- Antigen recognition, activation of TCR Vβ13.1 bearing T cells
- Peptide bound MHC molecules
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- Antigen References
1. Hong J, et al. 1999. J. Immunol. 163:3530.
2. Jason J, et al. 1997. Scand. J. Immunol. 45:81.
3. Chang JC, et al. 1995. Ann. NY. Acad. Sci. 756:370.
4. Miyahara E, et al. 1999. Anticancer Res. 19:2057.
5. Usuku K, et al. 1993. Immunogenetics. 38:193.
6. Bakakos P, et al. 2002. Clin. Exp. Immunol. 129:370.
- Gene ID
- 6957 View all products for this Gene ID
- View information about TCR Vb13.1 on UniProt.org
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