- FH6 (See other available formats)
- Regulatory Status
- Other Names
- CD15s, Stage-Specific Embryonic Antigen 1, SSEA-1, Sialyl Lewis X, sLex, sLe(x), Sialyl demeric LeX, Sialyl dermic Lewis X, Sialyl Lewis X-i, sLeX-i
- Mouse IgM, κ
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- Product Citations
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The FH6 antibody recognizes Sialyl Lewis X (demeric) on glycolipids or glycoproteins. It also recognizes Sialyl Lewis X with long carbohydrate attachments (Sialyl Lewis X-i). These antigens are expressed on human granulocytes, monocytes, small subsets of lymphocytes, some fetal tissues such as the fetal stomach, fetal colon, and fetal intestine, and a variety of cancer tissues. It is believed that these antigens are involved in cell adhesion.Product Details
- Antibody Type
- Host Species
- Purified 6B fucoganglioside absorbed to Salmonella minnesota.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
IHC, RIA - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
(PubMed link indicates BioLegend citation)
- Fukushi Y, et al. 1984. J. Biol. Chem. 259:10511.
- Fukushi Y, et al. 1985. Cancer Res. 8:3711.
- Kannagi R, et al. 1986. Cancer Research 5:2619.
- Kobayashi M, et al. 2010. Anticancer Res. 30:593.
- Product Citations
AB_2566069 (BioLegend Cat. No. 368102)
- Carbohydrate epitope; VI3NeuAcV3III3Fuc2nLc6.
Granulocytes, monocytes, subpopulations of lymphocytes, fetal stomach, fetal colon, fetal small intestine, and a variety of cancer tissues.
- Cell adhesion.
- Cell Type
- Granulocytes, Monocytes, Lymphocytes, Embryonic Stem Cells, Neutrophils, Neural Stem Cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
1. Fukushi Y, et al. 1984. J. Biol. Chem. 259:10511.
2. Kannagi R, et al. 1986. Cancer Research 5:2619.
3. Nakasaki H, et al. 1989. Cancer Research 49:3662.
4. Dohi T, et al. 1993. Anticancer Res. 13:1277.
- Gene ID
- 2526 View all products for this Gene ID
- View information about Sialyl Lewis X on UniProt.org
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