- MQ155 (See other available formats)
- Other Names
- Mucin-17, MUC3, MUC-3
- Mouse IgG1, κ
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- Product Citations
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It is a 451 KD glycocylated member of the mucin family with 2 EGF like domains on the C-terminus and serine/tyrosine phosphorylation sites on the cytoplasmic domain. It is expressed by epithelial cells and plays a role in cytoprotection, signal transduction. Expression of this molecule can also render tumor cells to become less adhesive. It interacts with PKDZ1 and increased expression of this molecule has been reported in colon cancer.Product Details
- Antibody Type
- Host Species
- Purified Recombinant Muc17 protein, Freund’s Complete Adjuvant
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2783313 (BioLegend Cat. No. 395302)
- 451 KD N-glycosylate single pass membrane protein
- Cytoprotection, extravasation, signal transduction
- Biology Area
- Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity
- Antigen References
- Malmberg EK, et al. 2008. Biochem J. 410:283.
- Gum JR Jr, et al. 2002. Biochem Biophys Res Commun. 291:466.
- Hirono S, et al. 2010. Cancer Sci. 101:259.
- Gene ID
- 140453 View all products for this Gene ID
- View information about MUC-17 on UniProt.org
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