Purified anti-human MUC-17 Antibody

Pricing & Availability
Clone
MQ155 (See other available formats)
Other Names
Mucin-17, MUC3, MUC-3
Isotype
Mouse IgG1, κ
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Product Citations
publications
MQ155_Pure_MUC-17_Antibody_112918
Human pancreatic cancer cell line (AsPC-1) stained with purified MUC-17 (Clone MQ155, filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG1, κ PE secondary antibody.
  • MQ155_Pure_MUC-17_Antibody_112918
    Human pancreatic cancer cell line (AsPC-1) stained with purified MUC-17 (Clone MQ155, filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG1, κ PE secondary antibody.
Cat # Size Price Quantity Avail. Save
395302 100 µg £168
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Description

It is a 451 KD glycocylated member of the mucin family with 2 EGF like domains on the C-terminus and serine/tyrosine phosphorylation sites on the cytoplasmic domain. It is expressed by epithelial cells and plays a role in cytoprotection, signal transduction. Expression of this molecule can also render tumor cells to become less adhesive. It interacts with PKDZ1 and increased expression of this molecule has been reported in colon cancer.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified Recombinant Muc17 protein, Freund’s Complete Adjuvant
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2783313 (BioLegend Cat. No. 395302)

Antigen Details

Structure
451 KD N-glycosylate single pass membrane protein
Distribution

Gastrointestinal tract

Function
Cytoprotection, extravasation, signal transduction
Interaction
PDZK1
Biology Area
Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity
Antigen References
  1. Malmberg EK, et al. 2008. Biochem J. 410:283.
  2. Gum JR Jr, et al. 2002. Biochem Biophys Res Commun. 291:466.
  3. Hirono S, et al. 2010. Cancer Sci. 101:259.
Gene ID
140453 View all products for this Gene ID
UniProt
View information about MUC-17 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/29/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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